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Neurofeedback as a remediation for late neurocognitive sequelae in survivors of childhood brain tumours: a pilot study

The aim is to study if Neurofeedback can be an applicable intervention.for survivors of childhood brain tumours. The QEEG wil be investigated whether under or overactive brainareas exist which can be trained. This study will also investigate whether…

Open-label, non-randomized, multi-centre positron emission tomography (PET) imaging study to evaluate a single dose of 250 MBq BAY858102 ([F-18]DPA-714) for its diagnostic potential in discriminating patients with probable Alzheimer's disease from healthy volunteers and to evaluate the radiation dosimetry of a single dose of 150 MBq BAY858102 ([F-18]DPA-714) in healthy volunteers

Based on the scientific background and knowledge as detailed above this clinical proof-of-mechanism study is performed in order to determine if PET imaging with [18F]DPA-714 has the diagnostic potential to discriminate probable AD patients from…

Genetic causes of 'TOS' (developmental language disorder)

With this study, we aim to shed light on the possible use of diagnostic next generation sequencing in DLD, by determining the diagnostic yield of WGS in this important class of neurodevelopmental disorder. In addition to determining this diagnostic…

Moses II - Measuring Elecsys β-Amyloid (1-42) II and Phospho-Tau (181P) in CSF Samples supporting Phase 2 Clinical Trial of 247AD201 (BIIB080)

The primary objective of the diagnostic study is to analyze the CSF measurements of β-Amyloid (1-42) (Aβ 42) and Phospho-Tau (181P) (pTau) using Elecsys β-Amyloid (1-42) CSF II and Elecsys Phospho-Tau (181P) CSF in the screening samples of the phase…

Detailed Speech & Language Phenotyping in SATB2-Associated syndrome

With this study we aim to define a detailed oral motor, speech and language profile for patients with SAS.