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The effect of oral ingestion of probiotics on the frequency and intensity of migraine attacks

To investigate whether probiotics can reduce incidence and severity of migraine attacks.

A Multicenter, Open-Label Study Evaluating the Long-Term Safety, Tolerability, and Efficacy of Monthly Subcutaneous Administration of Fremanezumab for the Preventive Treatment of Episodic and Chronic Migraine in Pediatric Patients 6 to 17 Years of Age

This study has been transitioned to CTIS with ID 2024-512837-34-00 check the CTIS register for the current data. Main objective:To evaluate the long-term safety and tolerability of subcutaneous test IMP in the preventive treatment of migraine in…

A Phase 3, Multicenter, Open-Label 156-Week Extension Study to Evaluate the Long-Term Safety and Tolerability of Oral Atogepant for the Prevention of Migraine in Participants with Chronic or Episodic Migraine

This study has been transitioned to CTIS with ID 2023-507096-21-00 check the CTIS register for the current data. To evaluate the safety and tolerability of treatment with atogepant 60 mg once daily when administered over 156 weeks for the prevention…

Treatment of headaches post-ECT with oxygen therapy; a proof of concept study

The purpose of the study is to investigate the effectiveness of oxygen therapy in headache after ECT.No research has been conducted into a non-medical treatment of headache after ECT. Oxygen therapy is potentially a quick, inexpensive, and safe way…

A Phase 3b Multicenter, Single-Arm, Open-Label Safety Study of LY2951742 (galcanezumab) in Patients with Episodic or Chronic Cluster Headache

The primary objective of this study is to evaluate the safety of open-label galcanezumab within the context of expected medical practice in eligible patients with episodic or chronic cluster headache. The secondary endpoints are to characterize the…