228 results
To compare acylated and unacylated ghrelin concentrations in pregnant women with GD and without GD.
In the present study we will evaluate the standardized care protocol developed in our outpatient clinic, intended to guide counselling for medication use prior to pregnancy. This protocol guides treatment decisions based on disease activity,…
To validate spectral analysis of the fHRV as a new method for fetal monitoring. To determine the exact influence on fHRV of several commonly used medicines in obstetric care; namely tocolytic drugs, corticosteroids, antihypertensive agents,…
The primary objectives of this study are to assess whether there is transfer of CZP into breastmilk of lactating mothers who are receiving an established dosing regimen of CZP by evaluatingthe concentration of CZP in mature breast milk, and to…
1a. Determine whether the effect of low-molecular-weight heparin can be explained by aspirin resistance. 1b. Assess the consistency of aspirin resistance during and after pregnancy measured with several complementary devices. 2. Determine…
We seek to elucidate the perinatal exposures to DEHP and BPA with the intention of providing evidence for policy makers and manufacturers. It is our hope that less toxic products will be used in health care and in the general population in the…
The aim of this study is to study risk factors (in the field of public health and occupation as well as medical technical factors) to enable early detection of pregnant women at increased risk and to integrate these risk factors in a risk prognostic…
Part I Preclinical study using the VIRTUAL preclinical prototype Primary objective:- To validate the reliability and applicability of regular use of the VIRTUAL (pre)clinical prototype in a bed-side setting (desktop) preconceptional and across…
With this research project we will investigate the relationship between SSRI concentration in the (pre)term neonate and clinical short and long term effects on the neonate after exposure to SSRI*s during pregnancy and lactation. Furthermore, the…
Cross-sectional study: To detect the normal range of amplitudes and segment intervals of the fECG. Case-cohort study: To compare the fECG between healthy fetuses and fetuses with various forms of severe CHD. To determine the diagnostic value of fECG…
The main objective of this study is to analyse the effect of preeclampsia on levels of memory T cell subsets in peripheral blood.
Developing a risk score based on established risk factors and personality traits, to predict possible postnatal anxiety/depression with or without problems in bonding between mother and child at the first consult at the midwives practice or…
To determine the feasibility of rs-fMRI in neonates undergoing a planned diagnostic MRI session following perinatal asphyxia. To assess intra-session reproducibility (test-retest reliability) of the rs-fMRI technique in neonates with asphyxia.
Primary Objective: To establish a prediction model for the probability of vaginal delivery and successful vacuum extraction at the second stage of labor, using the angle of progression by transperineal ultrasound. Secondary Objective(s): To evaluate…
The purpose of the sub-study is to do research into markers which will hopefully assist to diagnose the condition Peripartum Cardiomyopathy as early as possible. The blood donated for research will also assist in the assessment of women having a…
To obtain reference values of rsO2 of cerebral and muscle tissue measured by NIRO 200 NX for (relatively) healthy near term and term neonates.
To assess whether a higher prophylactic platelet transfusion threshold is superior to the lower thresholds in reducing the proportion of patients who experience a major bleed or death up to study day 28.
It is hypothesized that advanced hemodynamic monitoring will result in earlier detection of circulatory failure in critically ill newborn infants compared to clinical assessment of shock, which is the actual standard diagnostic tool in daily…
To compare the effectiveness of the tocolytic agents Nifedipine (a calcium channel blocking agent) versus Atosiban (an oxytocin receptor antagonist) in the improvement of neonatal outcome in women with threatened preterm labour (25-34 weeks…
The striking difference in uptake of Down*s Syndrome screening between countries that otherwise show close resemblance, particularly regarding healthcare policy, social and cultural factors (including non-directiveness of counselling, autonomous and…