63 results
The aim of this study is to study risk factors (in the field of public health and occupation as well as medical technical factors) to enable early detection of pregnant women at increased risk and to integrate these risk factors in a risk prognostic…
The main objective of this study is to analyse the effect of preeclampsia on levels of memory T cell subsets in peripheral blood.
Developing a risk score based on established risk factors and personality traits, to predict possible postnatal anxiety/depression with or without problems in bonding between mother and child at the first consult at the midwives practice or…
The purpose of the sub-study is to do research into markers which will hopefully assist to diagnose the condition Peripartum Cardiomyopathy as early as possible. The blood donated for research will also assist in the assessment of women having a…
The aim of the current study is to get insight into the in potential lifelong consequences of active disease and or prednisone use during pregnancy on the children of women with rheumatoid arthritis. As readout it uses indicators (risk factors) for…
The proposed study has 2 main aims: 1) Understanding the complex interplay of determinants of parenting and examining how specific parenting styles explain associations between parent characteristics (such as personality or mental and physical (ill…
1. To obtain early diagnostic and prognostic markers for preterm premature rupture of membranes and premature labour, based on ultrasound examinations of mother, placenta and fetus and markers present in blood and urine of mother at 11-14 weeks and…
The main goal of this study is to examine the clinical applicability of the Monica AN24*, for the use of this device in the LUMC for prolonged CTG-registrations in high risk pregnancies and particularly in monitoring fetal cardiac arrhythmias. The…
Immunodetection of Thyrothrophin (TSH) receptor in myometrium tissue.Furtermore the aim is to test myometrium tissue in vitro for it's relaxation and contractility and it's conductance of electropotentials.
The objective of this study is to better understand the forces and tongue movements that a baby uses while drinking at the breast and to what extent they contribute to effective feeding.
The objective of this study is to determine whether placental pathology is associated with early neonatal morbidity and the neurological development in late preterm infants.We hypothesise that more developmental pathology of the placenta will be…
The PRELHUDE study investigates the reversal of the ZAHARA3 study; whether subclinical congenital heart disease occurs in women who deliver prematurely for unknown reason. The biosamples taken during and after delivery will be used to determine…
Find en give answers on the following questions: If ASR does occur can this be correlated to the seriousness of the maximum partal sphincter dilatation and /or the congenital perineum length?
Aim of our study is to investigate the relation between prolactin levels and haemostatic changes during pregnancy
Evaluate the potential of these new parameters to identify small-for-gestational-age fetuses at risk of adverse outcome.
This study aims to explore the pattern of change in cardiovascular sympathetic activity in response to pregnancy by estimating the central sympathetic activity by measuring the pre-ejection period (PEP). The PEP is considered the golden standard for…
Primary objective: To determine whether the short-term neurological outcome of surviving children diagnosed with prenatally diagnosed ventriculomegaly is associated with the extent of VM before birth.Second objective: To determine whether the…
This study has two objectives:1) The first objective is to determine the frequency of mutations in NLRP7 and KHDC3L in patients with recurrent HM in the Netherlands.2) The second objective is to identify additional candidate genes associated with (…
To obtain a durable biobank of placenta, placental bed and myometrium, combined with a good clinical database. The tissue will be used to investigate differences in tissue specific expression between woman who have not gone into labour and deliver…
Objective #1: Implement clinical platform. We see the need to implement a clinical platform for two purposes. First, we want to design a biomarker profile of perinatal brain damage in human newborns (see above). Thus, we have established a…