27 results
Optimizing (breathing) techniques for radiotherapy of esophageal and lung carcinomas; a pilot study.
Primary objective: To determine the optimal breathing technique to minimize the dose to the heart of radiotherapy for esophageal and lung cancer using current photon techniques, without compromising the dose to the lungs. Secondary Objectives: 1. To…
Objective of the study is to evaluate efficacy of VZV vaccination in lung transplantation patients, intended to prevent morbidity by VZV infection. Efficacy of vaccination will be measured by means of determining cellular immunity to VZV. Cellular…
The present study aims at comparing a ventilation strategy with a lower tidal volume and a higher respiratory rate with ventilation using a higher tidal volume and a lower respiratory rate in ICU patients without moderate or severe ARDS.
The SIMBA project is a research collaboration in which children with asthma, their parents and healthcare professionals play an important role. The SIMBA study is a two year program that aims to develop and finally (pilot) test an exercise game that…
Primary objective: -to determine if there is a significant difference in the incidence of oxygen dependency at day 28 and/or death within the first 28 days of life between newborns with congenital diaphragmatic hernia treated with high frequency…
The first objective of this study is to evaluate by direct laryngo-tracheoscopy the possible role of cuffed versus uncuffed tracheal tubes in producing airway injury in infants and children who were previously more than 24 hours intubated. The…
The main objective of this study is to find a correlation between the rise in NT pro BNP level and the radiation dose given to the heart.
This study will investigate the feasibility of a hypoxic challaenge test (60 minutes duration). During this test the inspired air will have a oxygen content of 15%. This is a comparable value as is used during a commercial airline flight (ca 2500…
The objective of RAKKER2 is to study is, in terms of implementation, to get insight in the question 'to whom' a multifaceted primary prevention program should be offered. Therefore, in this study the predictive value of family history of…
The primary objective is to evaluate the percentage of the study population who have OSAS before and after treatment and the severity of it. A second objective is to correlate the prevalence of OSAS with different tumour sites and stages, as well as…
Experimental infections of humans with rhinoviruses, in particular rhinovirus 16 (HRV16) have proven to be a highly relevant and safe approach to study exacerbations in patients with asthma and COPD. The worldwide availability of stocks of HRV16 for…
To assess in the 4 GOLD stages of COPD:1) Performance based daily physical activity with respect tot the level, types and intensity of daily physical activity;2) Physical predictors for the daily physical activity status;3) Psychosocial predictors…
Primary Objective: to determine the feasibility of supported MV with low tidal volumes after partial neuromuscular blockade in patients with high respiratory drive. Secondary Objective: to determine the effect of partial neuromuscular blockade on…
In The Netherlands 2% of women and 4% of men suffer from Obstructive Sleep Apnea Syndrome (OSAS). NCPAP, the gold standard therapy for moderate to severe OSAS has been shown to reduce blood pressure in OSAS. NCPAP therapy is however hampered by…
1. To investigate whether the currently used hay fever forecast correlates with the symptoms that grass pollen allergic patients report directly using a new communication system that allows direct control, and whether the model can be improved.2.…
This study aims to investigate if there is a correlation between the severity of bronchoconstriction after an exercise challenge test 6h after a single dose of Qvar and after 4 weeks of treatment with Qvar, in order to know if the respons to a…
The primary objective is to determine feasibility of a home-based exercise program in a pilot study with patients with combined chronic pulmonary and cardiac disease.Secondary objectives are to evaluate patient satisfaction and changes in functional…
The aim of this study is to obtain further knowledge on aerosol droplet formation and spread during oxygen therapy.
Objective: To investigate the feasibility and acceptability of the online cognitive behavioral therapy program (eHealth CF-CGT), so that the program can be tailored to the needs of the patient
Objective of the study: Primary objective: to determine whether early discharge and out-of-hospital treatment of patients with low-risk acute PE (as defined by the inclusion and exclusion criteria) with the new oral factor Xa inhibitor rivaroxaban…