41 results
The specific trial aim is to establish whether the use of a high, dynamic 8-12 cmH2O PEEP level strategy to support the lung during stabilisation at birth, compared with a static 5-6 cmH2O PEEP level strategy, increases the rate of survival without…
Evaluate the safety and feasibility of providing automated tactile stimulation in response to apnea, bradycardia and/or desaturation using the BreatheBuddy.
To develop a prediction model for BPD using a range of multimodal predictors assessed in the first two weeks of life.
The aim of this study is to use diaphragmatic muscle activity measurements in premature neonates to develop an algorithm that can quickly identify that the patient has apnoea and then classify it by type (obstructive, central or mixed). This could…
To investigate oxidative stress levels in the plasma and urine of late preterm and term newborns treated for PPHN in the NICU.
The aim of this study is to visualize the position and movement of the vocal cords duringnon-invasive respiratory support of preterm infants after birth.
Investigate whether, in a routine clinical environment across a number of centers, the fabian-PRICO can adequately maintain oxygen saturation, with minimal staff intervention.
To determine the feasibility of umbilical PO for HR measurements after cord clamping in infants needing stabilization at birth and to compare this with standard PO on the right hand.
This study's first objective is to assess lung mechanics (measured with FOT) in mechanically ventilated infants, in the clinical practice of the NICU, with intermittent measurements during the entire period of mechanical ventilation. The FOT…
The objective of this study is to test whether the assays described above are feasible to predict bronchopulmonary dysplasia in premature infants.
This study has the following objectives:1) To assess if dEMG measurement is feasible during pulmonary transition in the delivery room* Does the signal quality (expressed in heart rate and respiratory rate) of dEMG during the transition agree with…
To determine the feasibility of measuring SpO2 and HR by applying a pulse oximetry probe to the umbilical cord at birth in term neonates undergoing PBCC.
To determine the accuracy of the *NeoBeat* device against gold standard measurements obtained by an ECG monitor with disposable (gel) electrodes and against pulse measured preductally as derived by pulse-oximeter.
To test whether performing a knee-to-chest flexion (KCF) manoeuvre is feasible directly at birth in infants born after elective caesarean section (CS) and leads to clearance of excess of lung liquid.Also safety parameters for mother and child will…
Primary question:Are dEMG measurements a clinical marker to assess the WOB in preterm born neonates?
In this research study we observe the effect of breathing on placenta- to infant transfusion, by measuring bloodflow in the umbilical vein, vena cava inferior, ductus venosus and hepathic vein, to get a better understanding of the underlying…
To test the safety and feasibility of a closed loop controller of the FiO2 based on the measured SpO2 in a NICU setting.
To determine the effect of MIST on the electrical activity of the diaphragm.
To design and test an EIT device and interface for infants based on a modified adult device (Continuous Regional Analysis Device for neonate Lung (CRADL) project). More specifically this protocol focusses on collecting EIT recordings in infants…
The primary objective of this pilot study is to determine the technical feasibility of the sensor in clinical practice. Accuracy is investigated with an agreement analysis of transcutaneous measurements and standard of care blood sampling,…