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Nebulising Amoxicillin-Clavulanic Acid in Patients with COPD (NACAP)

To investigate whether inhalation of nebulised amoxicillin clavulanic acid is effective in reaching amoxicillin sputum levels >= MIC 90 in patient with an exacerbation of COPD.

Open-Label Phase 2 Trial to Evaluate the Safety and Efficacy of;Aztreonam 75 mg Powder and Solvent for Nebuliser;Solution/Aztreonam for Inhalation Solution (AZLI) in Pediatric;Patients with Cystic Fibrosis (CF) and New Onset Lower Respiratory;Tract Culture Positive for Pseudomonas aeruginosa (PA)

The purpose of this study is to evaluate whether aztreonam solution for inhalation (AZLI) is safe and effective for the treatment and complete eradication of a lung infection with PA (Pseudomonas aeruginosa) in patients with Cystic Fibrosis (CF) and…

Pharmacokinetic evaluation and tolerability of dry powder tobramycin by a novel device in patients with non cystic fibrosis bronchiectasis

The first objective to investigate is the pharmacokinetics of DP tobramycin using the Cyclops® at four different dosages. The other objective is the local tolerability of DP tobramycin using the Cyclops® at four different dosages.

COVID-19: ultra-Low Radiotherapy Dose1: Colorado-1 trial

To determine the pre-liminary efficacy of ultra-low dose radiotherapy for COVID-19 related pneumonia with respiratory insufficiency.

Amoxicillin-clavulanic acid Levels in Sputum After Nebulization in AECOPD (ALSAN)

In this study we want to show adequate sputum levels are obtained throughout the day after inhalation of nebulized amoxicillin clavulanic acid in hospitalized AECOPD patients.