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Pressure and tissue deformation while using a regular and a newly developed soft-layered long spineboard.

The primary objective of this study is to evaluate if there are differences in the tissue-interface pressures, pressures inside the tissues and tissue deformation in the sacral area when volunteers lie on a regular spineboard versus a vacuum…

Patch-test cross-reactivity to a novel, probably non allergenic hair-dye precursor (PPD-derivative F000175918)

Objective: Determination of cross-reactivity to a newly developed PPD-derivative (F000175918) in previously PPD-sensitized patients. Hypothesis:Since PPD-derivative F000175918 is categorized as a moderate sensitizer, based on pre-clinical…

Thermal load of the 7 hill run

The primary goal is to examine the influence of weather condition on thermal load of an endurance run. Secondary we want to investigate the influence of fluid- and nutritional intake and clothing on thermal load of an endurance run.

The physiological strain during a time trial

The goal of the study is to registrate the cardiovascular, metabolic and thermalstrain during the participation of the WUCC time trial. Besides that we will look at different factors, like the weather, fluidintake and clothing, who possible have an…

Safety and efficacy of interleukin-1 inhibitor anakinra for the amelioration of fever during neutropenia and mucositis in patients with multiple myeloma receiving an autologous hematopoietic stem cell transplantation after high-dose melphalan

The primary objective is to evaluate the safety and efficacy of anakinra in patients with multiple myeloma receiving high-dose melphalan (HDM) in the preparation for an autologous hematopoietic stem cell transplantation (SCT). Secondary objectives…