18 results
Aim of this pilot study is to determine which intervention groups are feasible in a larger trial which aims to a compare postoperative pain and complication rates in moderate versus deep neuromuscular blockade, and normal versus low intra-abdominal…
The primary objective of this study is to investigate if the addition of bovine milk fat to an infant-formula product increases the diet-induced thermogenesis. Secondary objectives are to investigate if the addition of bovine milk fat in an infant…
The primary objective of the proposed study is to evaluate the effect of the high dose or L-arginine (3.0 gram) and a lower dose of L-arginine (1.5 gram) compared with a placebo supplement on postprandial vascular function, assessed by brachial…
• To determine the profile of CNS effects at several time points after 2 mg and 4 mg biperiden in comparison to placebo in healthy elderly subjects.• To investigate the safety and tolerability of biperiden in healthy elderly subjects.• To determine…
The first goal of the present research proposal is to investigate whether single session COMET imagery procedures, relative to no intervention control, increase the ease of recollection, the specificity, vividness and positive affectivity of…
To evaluate the diagnostic performance and safety of metal allergens proposed for inclusion in Metal Panel T.R.U.E. Test. The study will compare the diagnostic performance (primary) and safety (secondary) of ascending patch test doses of aluminum,…
To enhance our knowledge concerning the effectiveness of tDCS in the rehabilitation of stroke patients. Next to this, the results will also contribute to our knowledge concerning the role of the parietal cortex in episodic memory and attentional…
Primary objective: To accurately assess the direct functional consequences of high versus low phenylalanine levels in adult patients with PKU, using eye-hand coordination testing in tasks of different cognitive complexity. Secondary objective: To…
To examine whether L-arabinose addition to a sucrose drink will lower glycaemic and insulinemic responses in people at increased risk of developing type II diabetes.
To compare the digestion and absorption kinetics following the ingestion of sucrose plus arabinose versus sucrose only in healthy, young subjects.
Primary Objective: To verify the main effect of TDCS on brain excitability and the interaction effects of BDNF genotype and APLM latency on this main effect. Secondary Objectives: Compare different prediction models for the main effect of TDCS in a…
The main objective of the human dietary intervention study is to investigate the beneficial health effects of food products containing various combinations of an equivalent of 400 grams vegetables and fruits in healthy volunteers. This will be…
The purpose of this study is to investigate how quickly and to what extent different doses of EUapproved Tysabri® are absorbed and eliminated from the body (this is called pharmacokinetics) and how the body responds to different doses of Tysabri (…
Our primary objective is to compare the clinical outcome (time to and grade of symptom resolution) after 4-week-use of a whey based extensively hydrolysed formula (eHF) versus an amino acid-based formula (AAF) in children with nIgE-CMA. As secondary…
The objective of this study is to investigate the effects of stimulation of noradrenaline and acetylcholine and the blockade of NMDA-receptors on neural and behavioral measures of perception and consciousness.
The main objective of the study is to investigate whether ciprofibrate treatment can improve myocardial insulin sensitivity in subjects with IGM. As secondary objectives we want to investigate whether ciprofibrate treatment also improves diastolic…
Primary objective is the delta change in whole body insulin sensitivity upon Na-PB vs. placebo treatment. Secondary objectives are muscle mitochondrial oxidative capacity, muscle and liver fat content and energy metabolism.
This imaging methodology will allow an assessment of the extent of airway changes using a triple combination of Budesonide/Glycopyrronium/Formoterol Fumarate (BGF) and the dual combination Glycopyrronium/Formoterol Fumarate (GFF).