26 results
The aim of the study is to evaluate the safety of the Flex catheter and the effect of the renal denervation on blood pressure.
The primary objective is to study whether treatment with the mTOR inhibitor Everolimus results in an objectable change in phosphorylation of the selected downstream effectors 4eBP1 and p70S6K in human prostate cancer biopsies. A secondary objective…
ObjectiveInventory of the support and willingness of the visitors of the temples to participate. This study should be beneficiary in the development of a preventive program, focusing on depression. The primary outcome of this randomised trial is:…
To identify intraarticular parameters related to the initiation and course of development of articular cartilage lesions after knee trauma.
(1) How accurately do the TVS-CMD items reflect clinically relevant symptoms? (2) What is the concurrent and discriminant validity of the TVS-CMD? (3) How can the scoring system of the TVS-CMD be optimised?
To determine safety and efficacy of oocyte vitrification.
This pilot clinical trial has been designed to evaluate the safety and performance of the INSTRUCT scaffold, and to collect preliminary efficacy data
Primary goal:To investigate whether specific plaque characteristics are associated with ischemic lesions, especially (clinically silent) cerebral micro-infarcts, we will perform preoperative high resolution 3 and 7 Tesla MR plaque imaging in…
The primary objective is a) to study the occurrence of recurrent wheezing following hospitalisation for severe RSV LRTD, and to study the differences in occurrence between ventilated and non-ventilated infants, and ) to study differences in lung…
Our goal is to evaluate if this onsite assessment and aspiration during punction reduces inadequacy of specimens and see if onsite assessment by the aspirator is performed accurately after a brief instruction by a cytopathologist. Primary Objective…
First objective is to indicate neurocognitive outcome after mild traumatic brain injury in children. Second objective is to indicate prognostic factors for negative neurocognitive outcome.
The purpose of this clinical study is to provide confirmation of the clinical safety and performance of the CINCOR* System in patients at risk of developing CIN who are undergoing interventional percutaneous coronary procedures.Further, the data…
The objective of this study is to optimize the diagnostic strategy of atrial fibrillation in patients with stroke or TIA. There is no evidence-based guideline to diagnose AF in patients who have had a stroke or TIA. An objevtive related to this…
Main objective of this study is to test the safety and feasibility of MR-guided focal cryosurgery in newly diagnosed prostate cancer patients and in patients with recurrent prostate cancer after radiotherapy. Secondary objectives are: to determine…
see protocol
Objective: To test feasibility and safety of alpha beta T-/CD19 B-cell depleted allo-SCT in high risk or relapsed acute leukaemia / MDS followed by an innate donor lymphocyte infusion (iDLI)
This study will investigate frequency, types and associated distress of traumatic as well as harmful experiences during a hospitalization in a mental health clinic. Furthermore, this study will examine the relationship between trauma history and…
The study consists of three parts:a) Determine which specific components of a food allergen are important for (the severity of) the reaction.b) Developing a model to predict the severity of a food allergy using specific components (obtained from…
This study consists of two phases. For more information about the study layout, see page 13-16 of the research protcol.The aim of phase 2:- To compare two different sentinel node techniques in patients, suspicious for endometrial cancer. The main…
The objective is to determine the best surgical strategy for internal and external full thickness rectum prolapse in terms of morbidity, mortality, constipation, fecal continence, recurrence rates and quality-of-life of the treated individuals.