34 results
The primary aim of the phase I part of this trial is to establish the safety of a split dose regimen of Re-188-HEDP . The primary aim of the phase II part of this trial is to obtain insight in the efficacy of a split dose regimen of Re-188-HEDP , as…
Safety-evaluation in case of long term daily usage of MPC-7869. In this Open Label Study , with regard to the safety of MPC-7869, attention will be paid to the amount of AE*s, the physical examinations of subjects, the research of vital functions,…
The goal of this research is to determine whether multi-unit microneurography can be a practically useful technique for recording human muscle-afferent signals, and to determine which fiber types are present in the recorded signal to and from the…
To assess the performance of the ConforMIS for the repair of the osteoarthritic knee with damage in either the lateral or medial compartiment of the knee.
The primary objective is to determine the pharmacokinetic characteristics of galantamine after 2 single oral doses in children with Down syndrome. Secondary objectives are to evaluate safety and tolerability.
To answer the question, if the use of VEGF-R-TKI is associated with psychiatric side effects, and if so, to characterzie their symptomatology.
Primary1. To assess the major (complete/partial) cytogenetic response (MCyR) rateSecondary1. To determine the duration of MCyR2. To determine the complete hematologic response (CHR) rate3. To determine the complete cytogenetic response (CCyR) rate4…
In this trial we will investigate the following hypothesis:- Uremic vasculopathy develops, not only in large and medium sized conduit vessels, but also in the microcirculation.- There is a relationship between the rate of microcirculatory…
The purpose of this study is to evaluate accuracy of Cardiac Output measurements by comparing the Cardiac Output calculated by Arterial Pressure based Cardiac Output (APCO) and by other well accepted indicator dilution techniques, as well by…
1.) First, we hypothesize that a reduction of myocardial damage explained by lower levels of myocardial damage markers (e.g. troponin I, CK-MB) by sevoflurane may be related to a reduction of inflammatory mediators (i.e. TNF-α, CD11b/CD18 cells, and…
Objectives of the study are to evaluate the clinical applicability of the PeriFlux System 5000 and to investigate the reproducability of its measurements on inter- (and intra-observer) variability.
Determine the ADAMTS-13 activity in patients with a history of TTP.
Primary objective: To confirm the safety of the use of Urocell as a treatment for stress incontinence due to intrinsic sphinctre deficiency.Secondary ojectives: - To score the quelity of life with a standardized questionnaire and to score the level…
To examine the reproducibility and sensitivity of a new scoring system for pelvic floor muscle function
Primary1. To assess the hematologic response and return to chronic phase rate in patients with accelerate phase or blasts crisis whose diseae is resistant following treatment with at lest two BCR-ABL tyrosine kinase inhibitors when treated with…
To optimize a safe five-day intensive intravenous insulin treatment post stroke and to assess glucose profiles in patients with stroke and HG on admission, receiving standard continues enteral tube feeding.
Our goal is to acquire a practical, maybe even clinically useful microneurographic technique. In this research project, we will investigate the usefulness of multi-unit microneurography for the research of human muscle mechanoreceptors, by answering…
Comparing the reliability of a dietary-protein test with conventional Growth Hormone Stimulation Tests.
1. To estimate the one-year prevalence of neck pain among military pilots and aircrew.2. To determine the flight related and individual risk factors associated with this prevalence.3. To asses the cervical range of motion, the ability to return the…
To assess the long-term safety and tolerability (and in particular the infection occurrence) ofACZ885 in patients with rheumatoid arthritis (RA) who participated in the core CACZ885A2204,CACZ885A2206, or CACZ885A2207 studies.