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Single-centre, randomised, prospective, open-label, three-period, Phase 1 clinical trial for assessment of the pharmacodynamic and pharmacokinetic interaction of remimazolam and remifentanil

The primary objective is to quantify the remimazolam exposure-response relationship with and without remifentanil in regard to various stages of MOAA/S for procedural and ICU sedation and general anaesthesiaSecondary objectives are:- Quantification…