330 results
Objective The objective of this study is to assess which risk scoring model is most cost-effective for the discrimination between benign and malignant ovarian tumors that guides referral decisions for women with ovarian tumors in the Netherlands…
The goal of the study is 1) showing that EA, CA and perceived control are not stable but of dynamic nature and interact in predicting social anxiety symptom severity, 2) identifying possible mechanisms of change of CBT (the exact working of which is…
This study has been transitioned to CTIS with ID 2024-513412-10-00 check the CTIS register for the current data. Phase 1: • To determine the MTD/RP2D regimen of brigatinib monotherapy when administered in pediatric and AYA patients with ALK+ ALCL or…
The primary aim of the study is to assess the prevalence of MDRO carriage in patients undergoing ERCPs. This will be performed in four different countries with expected significantly different prevalence rates of MDRO carriage, namely: India, United…
Primary objectives1. To assess the safety of Tam added to Ven. Venetoclax will be dosed at 800 mg once daily. After 2 days of venetoclax, tamoxifen will be orally administrated in a ramp-up phase (2 days 10mg, 2 days 20mg, to a final dose of 40 once…
This study has been transitioned to CTIS with ID 2024-514233-37-00 check the CTIS register for the current data. To evaluate the feasibility and prove the concept of sentinel node biopsy in patients with carcinoma of the parotid gland and scheduled…
4D-CT examination to evaluate range of motion obstructions and underlying causes in scheker implants
Primary objective: To use 4D-CT to find possible relations between functional deficiencies of patients with an Aptis Scheker prosthesis and important prosthesis characteristics like implant placement and implant design.Secondary objective: To…
The main research goals in this protocol are 1) to determine whether disrupted extinction is also more common in patients with acquired brain injury (ABI) that are treated for anxiety and depression as in the previously studied anxiety population,…
Goal of the UMBRELLA Study is the optimization of existing MRI protocols and processing techniques required for MRI guided radiation treatment on the Marlin system (MRI of the MR-Linac) and diagnostic MRI scanners in the radiology department needed…
The aim of this study is to investigate the concept of fear of progression among advanced incurable cancer patients onongoing systemic treatment.
To compare OCT guided complete revascularization to the predefined objective performance goal (OPG) for all-cause death, stroke, myocardial infarction, or repeated revascularization namely 7% at 12 months. The OPG is derived from the most recent (9-…
We have defined the following milestones/deliverables for this project:1. Evaluation of IgG antibody response in pregnant women after participation in the Dutch national COVID-19 vaccination program.2. Evaluation of the relation between gestational…
This study has been transitioned to CTIS with ID 2024-514183-21-00 check the CTIS register for the current data. The primary objective of this trial is to determine whether, in subjects with moderately to severely active UC, treating to achieve a…
Our primary objective is to determine the prognostic value of parameters for early disease detection of familial pulmonary fibrosis in the study population. All putative parameters for detection of preclinical disease have been shown to be…
The main objective of this study is to assess effectiveness of the COVID-19 vaccinations, based on humoral (anti-coronavirus antibody) immunity, in GCA and PMR patients. Other objectives are assessing antigen-specific cellular (T-cell) immune…
Primary objective: -To assess the predictive value of post-PCI RFR (resting full-cycle ratio) and FFR (fractional flow reserve) with regard to SSR (suboptimal stent result) in CTO (chronic total occlusion) patients. Secondary objectives:- To assess…
This study has been transitioned to CTIS with ID 2023-507146-91-00 check the CTIS register for the current data. Primary Objective:• To evaluate the safety and tolerability of viltolarsen administered intravenously (IV) at weekly doses of 80 mg/kg…
In this study we aim to assess: 1.the diagnostic yield of endobronchial biopsy taken during HD videobronchoscopy in a large study population;2. the prevalence, visual pattern and specificity (for the detection of granulomas) of airway abnormalities…
To identify the characteristics on CLE images of the alveolar compartment in mechanically ventilated COVID19 patients with non-resolving acute respiratory failure.
To develop a non-invasive algorithm that allows the detection of LRPs with CTCA