318 results
Antireflux surgery is one of the most common major operations performed in pediatric patients. Most studies on the outcome of antireflux surgery in children are limited to retrospective data, case reports or are based solely on symptoms. A…
Our primary outcome is change in suicide ideation in patients. We hypothesise that, as a result of the improved skills and confidence of healthcare professionals in the experimental condition due to the intervention, suicidal patients are better…
we hypothesize that there is a link between gut microbiota composition and development of venous thrombosis.
Oral pazopanib once daily is safe and effective in advanced endometrial cancer for which no other therapies are available.
To assess whether temporary discontinuation of antihypertensive therapy in mildly cognitively impaired older patients on antihypertensive treatment improves cognitive and psychological functioning.
We aim to compare the effectiveness, feasibility and safety of both metformin and sitagliptin in patients with TIA or minor ischemic stroke and impaired glucose tolerance. We will assess whether a slow increase in dose of metformin and better…
Formalization of the current guidelines on VTE treatment duration with VKA, by means of using a VTE recurrence prediction model in patients with venous thrombo-embolism, will optimize its cost-effectiveness compared to care-as-usual. Only patients…
The purpose of our study is to compare the clinical effectiveness and cost-effectiveness of two treatment strategies of intermittent claudication (IC) due to an iliac artery obstruction: to start with supervised exercise therapy (SET) and deferred…
The first two exons of TRPV1 are deleted in the most common mutation found in cystinosis patients: A large 57 kb deletion. We aim to study TRPV1 expression in cystinosis patients both homozygous and heterozygous for this deletion.
We hypothesize that exogenous, enterally provided glutamine contributes substantially to the de novo synthesis of arginine in surgical patients. We hypothesize that aortic replacement surgery contributes to an alteration in arginine metabolism by…
Preoperative biliary drainage with metal stent in patients with resectable periampullary cancer results in less stent-related and drainage-related complications when compared to preoperative biliary drainage with plastic stents.
Breast cancer is one of the most common forms of female cancer worldwide. There are major limitations to the current imaging techniques that are used for diagnosing breast cancer. There is no single technique that combines an excellent sensitivity…
High dose of oral administration of omega-3 fatty acids ameliorates hepatic steatosis and insulin sensitivity in morbidly obese patients undergoing LRYGBP.
Evaluation of a population-based screening program for colorectal by repeated Fecal Immunochemical Test (FIT).
To assess the effectiveness of the Xience stent compared to the CYPHER stent in the PCI treatment of all patients in the MCL during 2007- 2008. This study runs parallel with the XAMI study.
To evaluate the usefulness of the VascuLuminator in children with a dark skin color that are obtaining a venous cannulation prior to elective non-cardiac surgery.
To assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols.
We hypothesize that helium postconditioning reduces ischemia reperfusion injury following an acute myocardial infarction and thereby reduces the size of infarction. Secondly, we hypothesize that this reduction leads to improved myocardial function,…
To investigate the effect of the two test products compared to the effect of the control product in infants delivered by Caesarian Section on the total bifidobacteria count of the gut microbiota.
Intensive counselling from a practice nurse in combination with varenicline (intervention group) will be significantly more effective in smoking cessation than a short quit smoking advice from a general practitioner in combination with varenicline (…