215 results
Kidney transplantation is the only treatment offering long-term benefit to patients with chronic kidney failure. Urological complications after kidney transplantation, such as urinary leakage and ureteral strictures, are associated with significant…
Health outcomes for people at risk of or suffering from non-communicable lung diseases in low-resource settings will be improved by developing capacity for implementation of evidence-based interventions for prevention, diagnosis and treatment in…
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…
To evaluate whether a dietary advice of green vegetables, beef and whole dairy products during six months including standard supportive care can decrease the TSH-level compared to standard supportive care alone in children aged 1-18 years with…
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
Background: Multiproblem young adults (between ages 18 and 27), characterized by a variety of severe psychosocial problems, comprise a societal challenge with high priority on the political agenda, both nationally and internationally. However, so…
Null hypothesis: the 8 centres with different cardiac rehabilitation (CR) programmes do not differ from each other with regards to the effectiveness.
We hypothesise that the diet over time has become healthier and more sustainable. Our current study was set up to (1) identify the differences in food consumption and nutritional quality over the course of 20 years in the Netherlands using the…
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
To investigate in an unselected memory clinic sample, the clinical value of 18F]FBB PET in terms of 1. change in diagnosis; 2. change in level of confidence of diagnosis; 3. impact on patient healthcare management.
Current standard treatments for symptomatic benign thyroid nodules (SBTN) are surgery or radioactive iodine. However, these interventions pose a risk to an otherwise healthy person. Therefore, minimally invasive alternatives have been explored.…
Prosody, both linguistic and emotional, is essential in the acquisition and usage of language and socio-emotional development, but it proves difficult for CI users because of their relative inability to hear spectral and, to a lesser degree, dynamic…
We expect maternal hyperoxygenation in the presence of fetal distress during labor to reduce abnormalities in the fetal heart rate tracing and to reduce the need for assisted birth or a emergency caesarean section without severe maternal or fetal…
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research
The aim of the project is to gain insight into the effects of centralisation of polytrauma care on the quality of care. We also want to investigate the effect on the quality and quantity of regular trauma care by shifting polytrauma care from…
Patients with obesity face many health issues such as obstructive sleep apnea (OSA). Prevalence of OSA may be as high as 70% in high-risk populations such as morbidly obese patients undergoing bariatric surgery. Although bariatric surgery itself has…
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
The dutch language version of the PRHWE and the Quick DASH questionnaire are valid to use in patients with hand and wrist complaints
The absolute bioavailability of oral imatinib (Glivec®) at steady state can be calculated using LC-MS/MS after concomitant administration of a single 100 µg microdose of stable isotope labeled imatinib (imatinib-d8).
It is hypothesized that implementation of the MASS protocol in IVE schools will increase the chances of obtaining a degree and a better chance of work employment in later life. An adequate approach to absenteeism using the MASS protocol at IVE…