1044 results
To determine whether fibrinogen concentrate infusion reduces perioperative blood loss and transfusion in patient experiencing clinically relevant microvascular bleeding during elective complex cardiac surgery and to determine whether its use is safe…
Our primary objective is to compare the short term (3 months follow-up) clinical and radiographic results of the Bledsoe Thruster Brace with the SofTec OA Brace in the management of patients with medial knee OA and a varus leg alignment.
Is the combination of pre- and intraoperative warming more effective in the prevention of perioperative hypothermia in comparison with intraoperative warming in patients undergoing elective surgery?
• Test the safety of the research drug, telcagepant (MK-0974)• Test the safety of the research study drug telcagepant (MK-0974) in the prevention of menstrually related migraines. • Compare the effectiveness of the research study drug telcagepant (…
3. TRIAL OBJECTIVES AND PURPOSE3.1 Primary ObjectiveThe primary objective is the prevention of actinic keratoses and squamous cell carcinomas by local application of MD-3511356 in comparison to standard sun protection measures in immuno-suppressed…
The food consumption survey aims to provide insight in the intake of energy, macro and micronutrients, and foodgroups by non-institutionalized elderly people (age 70 y and over) and the percentage of this population group that meets the nutritional…
The primary goal is to compare the physiological stress and strain of the fluid- and electrolyte balance and thermoregulation between participants of the Nijmegen 4-Day Marches that are hypertensive and use diuretics, and a group of healthy,…
We want to investigate the hypothesis that daily use of the above mentioned supplements (consisted of concentrated fruit en vegetables) results in improved healing of periodontal tissues in patients suffering from periodontitis. Besides we…
The main objective of this study is to assess the acute effect of co-ingested vinegar on postprandial plasma glucose levels in type 2 diabetes patients.
Our main objective is to determine the effect of HO-1 induction by heme arginate infusion on insulin resistance and endothelial dysfunction related to MetS. Secondary objectives are to determine the effect on adipose tissue, adiponectin plasma level…
The objective of this study is to test whether meat structure plays an important role in protein digestion, to maximise the amino acid availability and to stimulate the muscle protein growth in elderly people.
The first objective is to examine the impact of 4-month walking training on physical fitness, insulin resistance and cardiovascular risks in T2DM and their controls and to assess whether these effects are preserved 3 months after cessation of the…
Our aim is to compare the effect of 8-week exercise training and exercise training under hypoxia on vascular adaptations in function and structure, but also metabolic control (insulin resistance)
To investigate whether probiotics can reduce incidence and severity of migraine attacks.
The main objective of this study is to determine if the SPC has added benefits in optimising risk factors to prevent recurrent stroke, as compared with secondary prevention performed by the GP.
Considering the high prevalence of smoking and tobacco related deaths, knowledge about the appealing function (attractiveness) of tobacco additives is highly significant, because they promote the initiation of smoking. This part of the investigation…
To investigate the optimal timepoint of replanning during a curative radio(chemo)therapy in patients with Head and Neck cancer. Furthermore we like to analyze if the optimal timepoint of replanning is depending on tumorlocation, tumor volume or…
The objective of the study is to investigate effects of training on insulin resistance (IR), chronic heart failure (CHF) and cognition of resthome residents.