874 results
The current study aims to investigate the reliability of the AUDIT questionnaire in comparison to the PEth marker value in the general ED population. Thereby we would like to explore if there are advantages of using an objectified direct alcohol…
We hypothesise that using a continuous subcutaneous glucose monitor during pancreatic surgery, will significantly improve percentage of time spent in glycaemic target range (i.e. glucose ≥ 4 mmol/l and < 10 mmol/l).
This study aims to gain clarity on the issue of treatment for clinical levels of social anxiety in adolescents by testing the effectiveness of a group-based intervention. Most importantly, it aims to research the effectiveness of an added mHealth…
Primary objective To evaluate the Overall Response Rate (CR/PRrate) in patients treated with pembrolizumab for recurrent or progressive PCNSL after MTX-based first-line therapy To evaluate the safety of pembrolizumab in subjects diagnosed with…
To investigate if patient controlled sublingual sufentanil tablets as compared to patient controlled intravenous morphine lead to improved independent mobilization on postoperative day 1 after laparoscopic donor nephrectomy (LDN).
The aims of this study are (1) to determine if ear absorbance can be used to non-invasively measure ICP and (2) to determine if ICP differs between glaucoma patients and controls.
Primary Objective: Non- invasive determination of the oxygenation values and the haemoglobin concentration of retinal arteries and veins by means of retinal imaging.
The primary objective of this study is to investigate if exogenously supplied ELABELA can induce MZ twinning in cultured human embryos. This will be done using time-lapse monitoring of donated human embryos that will be treated with synthetic…
Safety:* Evaluate the safety of AVXS-101 through incidence of adverse events (AEs) and/or serious adverse events (SAEs)* Evaluate the safety of AVXS-101 based on the change from baseline in clinical laboratory parametersEfficacy objectives will be…
Primary: to determine if inhibition with GPB can provide a significant (>30%) reduction in the accumulation of orally administered Iodine-123 in salivary glands, measured at 4h after administraion. Secondary: to determine if a reduction at 4h…
This is an exploratory validation study in a small group of subjects receiving a CI to verify if ECoG measurements with AB*s novel ECoG system are useful as an intra-operative tool for soft surgical techniques to spare residual hearing. This trial…
To determine whether DUX4 can be detected in epithelial or stem cells isolated from midstream urine and/or buccal brush biopsies and/or skin punch biopsies of FSHD patients. Hereby we will assess whether any of these biomaterials can be used as an…
Thermoregulation in patients with spinal cord injury and cold sensations, an explorative pilot-study
To investigate whether SCI patients with regular complaints of cold sensations in daily life have more impaired thermoregulatory responses to changes in environmental temperature compared to SCI patients who do not have these cold sensations in…
Evaluate whether CT lung densitometry and PWV associate with plasma DES concentrations. In addition, we want to determine whether certain other laboratory determinations in the blood and condensed exhalation vapor correlate with plasma DES.
The primary objective of this study is to investigate if shear-wave elastography and contrast-enhanced ultrasonography can identify those patients most suitable fir an intervention (surgery or endoscopic balloon dilation) and those patients that…
The collection of data of the orofacial motor skills with the OMOK in healthy children between 2 and 8 years.
To assess the presence of absence of ILCs in preclinical (early) pSS biopsies as well as to assess their potential interaction with epithelial cells.
We aim to prevent or reverse developmental regression in patients with Kleefstra syndrome. We hypothesise that the regression we observed is the result of a psychotic disorder, which isnot properly recognised by clinicians and often not treated…
The primary aim is to assess myocardial development and function of the left ventricle in fetuses with the suspicion of aortic coarctation on fetal echocardiography. The secondary aim is to study left ventricular blood flow movement with vector…
Taken together, social performance monitoring processes and empathic abilities are key ingredients for efficient social behavior. Possible disturbances in these processes may severely inhibit or even impair social interactions with possible long-…