62 results
Assessing the value of online education with and without remote monitoring added to standard perioperative bariatric care
Monitoring and evaluation of the Dutch guideline for treatment of aHUS in children and adults during two years.
To study wether a biodressing impregnated with polyhexamethylene biguanide in the treatment of spoke injuries in children could give a reduction in pain during the treatment compared to the standard treatment with wound dressing impregnated with
The objective of the LEOPARD-2 trial is to assess the safety of MIPD versus OPD and after that to assess the time to functional recovery of MIPD versus OPD for symptomatic benign, premalignant or malignant peri-ampullary disease.
To investigate effectiveness of spinal chloroprocaine, and prilocaine in day case surgery. The null hypothesis is that there is no significant intergroup difference in complete recovery from motor blockade.
The purpose of this study is to provide insight in to what extent clinically significant systemic absorption of tobramycin occurs (resulting in a serum tobramycin concentration> 1.0 mg / L) in ICU and Medium Care ICU patients who are being…
To document that 8 weeks treatment with ledipasvir-sofosbuvir is effective in chronic HCV genotype 4 patients without cirrhosis.
The aim of the present study is to investigate the added-value of reduction of early signs of spasticity in the upper extremity on improving functional arm-hand skill performance in sub-acute stroke patients with either a severely or moderately…
To investigate whether bright light therapy is an effective treatment for depression during pregnancy compared with low-intensity placebo light therapy (proof-of-principle) and to investigate the late effects of bright light therapy versus placebo…
Aim of this study is to determine the functional outcome after a minimum of 1 year follow-up after fixation of the fractured olecranon with TBW or PF. Subgroup analyses will be done to investigate the assumed advantage of PF compared to TBW in…
Primary Objective: The main objective is to investigate the effectiveness of PRT compared to CAU in school-aged children and adolescents with ASD.The primary research question is:1) Directly after treatment and at follow-up, what is the…
To determine the resorption of ropivacaïne and serum concentration we need 6 bloodsamples at t=0, t=30 min, t=1 hour, t=2 hour, t=4 hour, t=8 hour. A pharmacokinetic model will be made for each procedure using a software package MW/Pharm © (version…
Primary Objective: To study the effect of PNT and structured physiotherapy on function and pain of patients with lateral epicondylalgia.Secondary Objectives: To study the effect of PNT and structured physiotherapy on quality of life, patient…
Primary objective is to demonstrate a 25% reduction of the active irinotecan metabolite, SN38, in healthy liver tissue in patients with mCRC or other solid tumors as a result of preceding dietary restriction five days in advance. Secondary…
The main aim of the current study will be to assess the effect of acute blood flow restriction and blood flow restriction combined with resistance exercise on the muscle protein synthetic rate in healthy young male subjects
To demonstrate that the use of US-accelerated catheter-derived thrombolysis in patients with recently (less than 7 weeks) thrombosed infra-inguinal bypass grafts or native arteries with half the dose urokinase (50.000 IU/h) will significantly reduce…
To test the effectiveness of the optimized versions of an online alcohol moderation (AM) and smoking cessation intervention (SC) in samples of alcohol misusing or cigarette smoking cancer survivors, in comparison to control conditions (internet-…
The primary goal of this study is to assess the feasibility and acceptability of the worry reduction intervention among MUS-patients and GPs as implemented in primary care. A second important goal of this study is to assess the feasibility of…
Objective: The purpose of this study is to compare the diagnostic surgical rate of a matched control group, derived from a retrospective review of patients without GEC testing, with a prospective GEC tested group.
The objective is to assess the safety profile of the hypothermic Airdrive* oxygenated machine perfusion system for graft preservation in kidney transplantation.