24 results
Studies of ex vivo muscle cell autophagy flux, leucocyte mitochondrial function and oxylipins, specifically prostaglandin E2 (PGE2) in critically ill patients during admission to an intensive care unit (ICU).
To investigate the effect of Bifidobacterium lactis CECT 8145 BPL1® on the seroconversion rate after influenza vaccination in healthy adults, compared to placebo treatment.
Objective: The primary objective of this pilot project is to investigate the early course of motor development in children with DS. Secondary objectives are to investigate the relation between type of SCN1A mutation and developmental profile and to…
To prospectively evaluate the diagnostic accuracy of dynamic cardiac CT in addition to and in comparison with TEE in unselected patients with a clinical suspicion of native valve endocarditis.
The aim of the here proposed study (BLOC-II) is to clarify whether cardiac function in survivors of BC should be monitored by GPs. We expect to clarify whether an unselected population of long-term BC survivors is at increased risk of developing…
1. study the effects of an 8-week high-intensity interval training on motor and non-motor aspects (primary outcome: anxiety and depression) of Parkinson's disease and Multiple Sclerosis, compared to traditional continuous aerobic training and…
The purpose of this study is to expand the so far limited research on the effectiveness of ImRs in the treatment of OCS. The primary objective is to investigate whether the application of ImRs, after previous outpatient ERP treatment, leads to…
The overall aim of the study is to develop innovative minimally invasive monitoring techniques that can identify lung inflammation in pwCF when using highly effective modulators, compared to patients whom are not eligible for CFTR modulators (…
To prospectively evaluate the (cost)-effectiveness of LITT plus chemoradiation therapy (CRT) vs. CRT alone in patients with primary irresectable glioblastoma (GBM).
The objective is to obtain insight into a dose-dependent effect of vitamin K2 on oxidative stress and specific markers of the immune system. The primary objective is to investigate the effect of vitamin K2 on oxidative damage to lipids by measuring…
To study the effectiveness of a blended intervention, focused on personal feedback and coaching regarding physical activity and protein intake, after hospital discharge in patients who have undergone elective GI or lung cancer surgery on the outcome…
The objective of this study is to collect additional data on the safety and performance of the slowly-resorbable TIGR® mesh in patients undergoing TEP for IGRP.
Primary Objective: - To examine whether a 12-week Mediterranean Diet (MeD) intervention reduces white adipose tissue (WAT) inflammation or fat droplet size in the rectal submucosa in patients with BMI >= 25 kg/m2 who have undergone an…
1. Primary Objective The primary objective of this study is to assess the effect of lanifibranor alone compared toplacebo and the effect of lanifibranor in combination with empagliflozin compared to placeboon HbA1c after a 24-week treatment duration…
To evaluate the efficacy of two doses of norucholic acid vs. placebo for the treatment of primary biliary cholangitis (PBC) in patients with an inadequate response to ursodeoxycholic acid (UDCA).
Assess the percentage of responders to hepatitis B vaccination (i.e. attaining anti-hepatitis B antibody titres beyond 10 IU/L) in healthy elderly receiving a daily dose of OPN-10, compared to a placebo product.Secondary objectives:• Compare the…
The primary objective is to measure the effect of nociceptive stimuli on features derived from ECG, ABP, PPG, EEG and facial video recordings, to be used to design an index of nociception. The index of nociception should correlate well with strength…
We aim to compare EMR and ESD for removal of visible lesions in Barrett*s esophagus.
To assess the efficacy of treatment with Endocalyx for chronic heart failure.
COHORT 1Primary objective: • To assess the safety and tolerability of IV administration of EI 201 as monotherapy in subjects with incurable R/M HPV16+ oropharyngeal and anogenital tumors and to select a starting dose of EI-201 for Cohort 2 Secondary…