101 results
To assess and compare long term scar quality of deep dermal burns after debridement with hydrosurgical- and conventional tangential excision.
The primary objective of this study is to determine if ambrisentan is effective in delaying disease progression and death in subjects with IPF.Secondary objectives include evaluation of the safety and effect of ambrisentan on development of…
The objective of the trial is to assess the safety and tolerability of i.c.v. administration of sNN0029 infusion solution at a dose of 4 µg per day delivered via a Medtronic SynchroMed® II Infusion System.
Primary obejective is the evaluation a ventral patch is associtaed with less complications than a conventional mesh for epigastric and umbilical hernias. Complications are defined as unexpected events necessitating a treatment within the period of…
To determine if orteronel plus prednisone improves radiographic progression-freesurvival (rPFS)To determine if orteronel plus prednisone improves overall survival (OS)
Since October 2010 the Catharina-hospital in Eindhoven offers a cardiac rehabilitation program to cardiovascular patients. As an optional section of the program an adjusted training of MBSR is offered, called *stress reduction in cardiovascular…
The study will assess the safety of a sex hormone (levonorgestrel) releasing T-shaped intrauterine contraceptive system in female adolescents under 18 years of age. The incidence of adverse events over 12 month treatment period will be the main…
Investigation of the effect of interpretive bias modification on anxiety levels in dental phobia. If CBM-I indeed has positive effects in the treatment of dental phobia, it could be integrated in the treatment-as-usual as an additional intervention…
The study objective is to evaluate the clinical outcome of percutaneous aortic valve implantation in consecutive *real world* patients with severe aortic valve stenosis intended to be treated with the Medtronic CoreValve System.
The primary objective of this clinical investigation is to assess the safety and effectiveness of the Perceval S-valve at 12 months after implantation when used to replace a diseased or dysfunctional aortic valve or aortic valve prosthesis. The…
A new surgical device for the creation of compression anastomoses, the ColonRing*, which is nickel- titanium based, has been introduced. Safety and efficacy of the device have been established in previous clinical studies and the device has been…
Te demonstrate that the use of US-accelerated catheter-derived thrombolysis in patients with recently (between 1 and 7 weeks) thrombosed infra-inguinal bypass grafts or native arteries will significantly reduce (at least 12 hours) therapy time…
The aim of the present study is a performance evaluation of INNOVANCE® PFA P2Y. The first objective is the determination of a reference interval for the Intended Use Population (patients eligible for Clopidogrel therapy). This will be done by…
1º Is there a significant difference of more than 10% in the pharmacokinetic parameter AUC of the investigated antineoplastic drugs (as a surrogate parameter for the efficacy) in the presence and absence of NNRTIs and/or PIs?2º Are there clinically…
There is a double study objective:- First the effects of a PRP-injection in the treatment of the jumper's knee in comparison with the effects of a placebo injection - Second the effects of a PRP-injection in comparison with the effects of an…
To compare the HM to bipolar resectoscopy for removal of smaller type 0 and 1 myomas in terms of efficiency and complications.
This pilot study examines the effects of supplementing the standard treatment interventions to improve mobility with modified supervised exercise therapy together with improvements in cardiovascular risk management by using an intensive risk factor…
In this study, we want to find the anesthetic technique with the highest patient satisfaction, best surgical and anesthesiological conditions and the technique with the highest time efficiency. We compare three anesthetic techniques.
To investigate if endoscopic transgastric necrosectomy will lead to a reduction ofthe per- and postoperative pro-inflammatory response, as compared to necrosectomy by laparotomy, in patients with infected (peri-)pancreatic necrosis.
The primary objective of this study is to evaluate safety and efficacy of the BIOTRONIK PRO-Kinetic coronary CoCr-stent in patients with single de novo lesions of native coronary arteries.