12 results
To study the long-term effects of interferon-α treatment for chronic hepatitis B patients infection.
Primary Objective: to investigate whether half-dose PDT treatment leads to a higher percentage of cCSC patients with SRF on OCT at baseline, achieving an absence of this SRF on OCT as compared to eplerenone treatment.Secondary Objectives: to…
To evaluate whether YCF with added scGOS/lcFOS and n-3 LCPFUAs can decrease the number of upper respiratory tract infections compared to cow*s milk in children aged 12-36 months with recurrent upper respiratory tract infections.
The main focus of the present proposal is a first step towards treatment intensity de-escalation in older breast cancer patients. For this, we propose to initiate the first TOP consortium study (TOP-1) that will study the effect of omitting…
Clinical feasibility of the urine collection device, indicated by staff and parents.
The primary objective of this study is to:• Determine the safety and tolerability of AG-120 and AG-221 when administered with induction and consolidation therapy in patients with newly diagnosed acute myeloid leukemia (AML) with an isocitrate…
To collect long term outcomes on the use of the Neovasc Reducer
• AIS is a chronic condition of the back. Once the curvature shows progression and exceeds a Cobb angle of about 20 degrees, chances are small that this curvature will disappear spontaneously.2 There is little epidemiological data of the Netherlands…
Primary Objective: To optimize the current DBS-treatment of advanced PD. For the primary objective the following research questions will be answered: By performing STN DBS under general anesthesia, will there be a significant reduction in cognitive…
To evaluate the safety and performance of the MobiusHD system in subjects with resistant hypertension. Substudy HF:As above, and obtain an initial understanding of the efficacy of the MobiusHD System on cardiac performance and functional status in…
The primary objective is to determine whether adjuvant treatment with natural dendritic cell (nDC) vaccination, after complete radical lymph node dissection or sentinel node procedure in stage IIIB and IIIC melanoma patients, improves recurrence-…
The proposed study aims to examine the antidepressant efficacy of oral S-ketamine augmentation in patients with TRD treated with regular antidepressants in a double-blind randomised controlled trial. Secondary questions involve the effects of oral S…