34 results
This study will be a prospective, placebo controlled, randomised phase 2 single centre study with the primary objective to evaluate the safety and tolerability of 2-IB when administered to patients with AIS due to LVO, treated with IVT and/or EVT.…
Primary objectiveThe primary objective is to evaluate whether a standard pre- and postdilatation of the modern DES results in a more optimal stent implantation compared to DS as evaluated by OCT in patients with stable coronary artery disease.…
In this trial we will study the utility of PerfusiX-Imaging for perfusion assessment of the gastric conduit in comparison with the standard of care.
To confirm our STARNL-1 pilot efficacy and safety data in a larger cohort and obtain insights in the mechanism of action by evaluating electro-anatomical alterations of stereotactic arrhythmia radiotherapy in patients with therapy refractory…
In the present study, we propose to investigate the efficacy of pharmacological treatment of GDM (using metformin) by the pathophysiological cause of hyperglycemia, namely reduced insulin sensitivity or reduced insulin secretion. Primary Objective:…
To establish the safety and effectiveness of the Edwards SAPIEN 3/ SAPIEN 3 Ultra Transcatheter Heart Valve (THV) in subjects with moderate, calcific aortic stenosis (AS)
The primary objective of the study is to determine feasibility of CEA assessments at home using (automated) capillary sampling. Home based (automated) capillary sampling will be considered feasible if a success rate of 85% or greater has been…
The primary aim of this RCT is to evaluate whether the use of oral supplementation of hydrolysed collagen/vitamin C in addition to usual care (education, load management and PTLE) is superior to usual care and placebo on VISA-P score after 24 weeks…
Primary Objective: The main goal of this study is to provide evidence that steering saccharolytic/proteolytic fermentation by a specific indigestible fibre mixture supplemented against the background of a high-protein diet optimizes beneficial and…
Primary Objective:• To evaluate the effect of an online 12 week plant-based dietary program compared to usual diet on change in glycated hemoglobin and estimated relative CVD risk in persons with type 2 diabetes. Secondary Objective(s): • To…
Primary Objective: Assess the ability of MRCP+ and LMS to detect change in total biliary volume and cT1 value, 8 weeks after endoscopic treatment of dominant strictures, by a clinical decision rule.Secondary Objective(s): Assess natural course of…
Primary Objective:To assess the effect of a 12-week moderate-vigorous intensity exercise intervention in fatigued IBD patients with quiescent disease on fatigue and health-related quality of life (HRQoL) (short term, measured at 3 months).Secondary…
In this trial we will study the utility of PerfusiX-Imaging for the identification of intersegmental planes during thoracoscopic segmentectomy.
To investigate the effects of ICIs (anti-CTLA4, anti-PD1, combination anti-CTLA4/PD1) on vascular inflammation (PET-CT) in stage III melanoma patients. We hypothesize that the increase in vascular inflammation will be greater in the exposure group…
1. Mapping the effects of pain education on pain perception and psychosocial functioning of patients with CRPS.2. Further optimize the quality of care for patients with CRPS by further exploring the possibilities of a pain education program.
Objective: This protocol describes a framework that will be used to create different studies. The general primary and secondary objectives of this protocol are stated below:Primary objective: Investigate the effect of surgery on the position and…
To evaluate the validity of grip work and self-perceived fatigue measured with the eforto® system for monitoring hip fracture recovery and insight in resilience.
The primary objective will be to evaluate the sensation of the keloids as measured by Semmes-Weinstein monofilaments (SWM), Pressure Specified Sensory Device (PSSD) and/or Quantitative Sensory Testing (QST), compared between patients with and…
To determine early and subtle MRI changes in premanifest and early manifest HD patients which distinguish them from the healthy population. This includes both structural/quantitative MRI data and MRI-signs of blood-brain barrier (BBB) breakdown. And…
The main objective of this study is to determine how well the Multiple Screener© can differentiate between patients with no cognitive deficits, mild cognitive deficits and cognitive impairment. Additionally, we aim to confirm the observed accuracy…