43 results
We aim to fill up the present gap in knowledge about HCO3- and mucus transport in native human intestine, and about possible effects of pharmacological correctors on these parameters in CF, by detailed electrophysiological and biochemical ex vivo…
To identify the pathophysiology and predictors of study (extreme) cancer treatment -induced cardiovascular toxicity in cancer patients, by in vitro investigation of cardiovascular toxicity in patient-derived cardiomyocytes (iPSC-CMs) and endothelial…
To assess swallowing and speech function in patients ten years after CRT for head and neck cancer with preventive rehabilitation in order to compare these results with those after six years and to those of patients after CRT without preventive…
Objective of this study is to determine the prevalence of vitamin B12 deficiency among patients who underwent esophagectomy with GTR. The following specific research questions heve been defined:- What is the prevalence of vitamin B12 deficiency in…
The determination of the energy expenditure in wheelchair-bound children in rest, during daily activities, and during therapeutic horseback riding.
To compare dose homogeneity and heart and lung doses in supine and prone position. Furthermore, the reproducibility of prone position will be compared to standard supine position, and we aim to identify those patients who benefit most from prone…
To gain insight into individual differences in sensitivity of the circadian system. In vivo measured by the sensitivity of melatonin suppression, thermoregulatory processes and psychological functioning to full spectrum and blue reduced light, and…
Primary: Assessment of the short-term effect of a Heat and Moisture Exchanger on tracheal mucociliary clearance in laryngectomized individuals. Secondary: The relationship between clinical assessment, ciliary activity and mucociliary clearance.
Primary:Assessment of the effect of preventive versus on demand nutritional advice and a nutritional supplement (a daily energy- and protein-rich evening snack) on weight loss of patients receiving standard antiviral therapy with PEG-interferon in…
HypothesisChildren and adolescents with non-psychotic psychiatric disorders represent a vulnerable group high prone for psychotic symptoms. In contrast with normal populations more pronounced symptom and cognitive profiles will be found predicting…
Aim of the research is the development and evaluation of an intervention to promote the sexual and reproductive health of adolescents who differ in cultural background. Fundamental idea is that sex education is more effective if the information is…
In this trial, current usual care concerning cardiovascular education is described. Second aim is to study what is understood of this education by the patient. Last aim is to study what effect training of GP's on this subject will have on the…
Characterization of T cell responses in young children after influenza infection
Riskreduction of developing breast carcinoma by means of better surgical techniques (removing all normal breast tissue).
The primary goal of this study to investigate the long term functional and radiological outcome of those patients that underwent a cervical laminectomy in the treatment of a cervical spondylotic myelopathy.The secondary goal is to determine those…
The objective of this study is to get insight in the effect of the Cardio Thoracic Harness for men and the Cardio thoracic bra for women. The harness and the bra possibly have an important role in pain management. The producer of the harness and the…
1. To detrrmine the applicability of standard energy expenditure prediction equations for accelerometry in measuring physical activity in children with musculoskeletal and other chronic diseases (see below).2. To develop disease specific prediction…
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The aim of this study is to explore whether changes in parameters of physical activity, physical fitness and mentally stimulating activities are associated with cognitive parameters.
To further investigate the photoprotective properties of melanin and the role of skin-infiltrating neutrophils with respect to the damaging effects of solar radiation on human skin.