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Endothelial cell loss in pseudophakic patients receiving a Paul glaucoma drainage device with its tube inserted in the anterior versus posterior chamber: a randomized controlled trial

Primary: to determine the loss of corneal endothelial cells after implantation of a Paul GDD with its tube either anterior or posterior of the iris. Secondary: to compare efficacy and safety of both procedures.

Comparing the Baerveldt and Paul glaucoma drainage devices and their effects on the corneal endothelium

To detemine whether the Paul tube induces less damage to the corneal endothelium than the Baerveldt GDD.

MOODSTRATIFICATION IMMUNOSTRATA Groningen
Premature immune ageing and spinning therapy in mood disorders

Primary objective:To assess whether the state of premature immune ageing (senescent CD8+ T cells) modify treatment response to physical endurance intervention therapy in depressed patients. We will compare the mood-beneficial effects of physical…

'A clinical study of the difference in the effect of pocket-irrigation in the treatment of peri-implantitis compared to a conventional therapy, the airflow: a randomized controlled trial'

The aim of this study is to assess the effectivity of the Fluxion, in combination with Bluem (Bluem, Bluem Europe, Zwolle, The Netherlands) and in combination with demineralised water. This aims to find a minimally invasive treatment for peri-…

A prospective, multi-centre, repeated measures, traditional feasibility study investigating neural health correlates with outcomes and evaluating focused multipolar implementation in the Phoenix Research System for newly implanted adult cochlear implant recipients.

This traditional feasibility study intends to inform a future pivotal trial in the following two ways. Firstly, it aims to evaluate the potential of neural health metrics triggered by FMS, to predict the implant recipient*s auditory performance -…

Self-management of stress and sleep disturbances with eHealth applications for people with burn-out, mood, anxiety or psychotic disorders

To test the effectiveness and cost-effectiveness of adding VRelax to treatment as usual (TAU) in improving functional and symptomatic outcomes in patients with anxiety, bipolar, burn-out, depressive, psychotic or post-traumatic disorder compared to…