18 results
To investigate the use of a temporary peginterferon alpha-2a add-on strategy during entecavir therapy in patients with HBeAg-positive chronic hepatitis B by comparing the efficacy of this regimen versus entecavir monotherapy.To evaluate the long-…
The objective of this research is to investigate in vivo by means of RSA the amount of wear of the insert very secure.Through frequently taken RSA measurements over a 3 year period, we might be able to predict the longevity of the XLPE insert.
To determine the optimal therapy for patients with pT1-2 pN0 oral and oropharyngeal cancer
A clinical research study to find out if Xolair is safe and has beneficial effects in adolescents (12 years old and above) and adults with cystic fibrosis (CF) and ABPA. All patients entering the study will be taking oral corticosteroids (steroid…
Comparison of the accuracy of achieved correction of the mechanical axis in the frontal plane relative to preoperative planning, endeavouring to achieve an overcorrection of a varus malalignment to 3-4° of valgus, comparing open and closed HTO*s.
Aim of this study is to determine the effect of isoflurane versus sevoflurane on blood pressure and systemic vascular resistance.
The objective of this extension study is to assess the long-term safety and efficacy of Myozyme treatment in patients with Late-Onset Pompe Disease who were previously treated under the placebo-controlled, double-blind study AGLU02704.
The primary objective of this study is to compare the efficacy of wet wrap therapy with diluted corticosteroids versus wet wrap therapy with emollients. The secondary objective is to develop an effective and objective value for monitoring the…
To compare the efficacy of autologous platelet concentrate injections with corticosteroid injection in patients suffering from plantar fasciitis with respect to pain and function.
The objective of the study is to karacterize Pharmacokinetics and pharmacodynamics of frequently and routinely used drugs in children and neonates undergoing ECMO treatment and ultimately to formulate dosing regimes for these drugs for patients…
This study aims to investigate the reaction of the peri-implant tissues to these materials when used in oral implant dentistry.
With the goal of improving kidney function and without causing an increased number of rejections, is it possible to reduce tacrolimus dosage through the use of the previously-mentioned immunosupressives after month three.
1. IS there an effect of short-time combined use of NSAIDs and diuretics/RAAS-inhibitors on the heart- and kidneyfunction in orthopaedic patiënts who undergo a total knee- or hipreplacement.2. Is cystatin C a better endogenous marker of kidney…
To investigate whether addition of PEG-IFN alfa-2a in HBeAg-negative chronic hepatitis B patients who are pretreated with NA enhances the degree of HBsAg decline
In this study, we will test whether STN-DBS related apathy can be reversed by switching stimulation to a more dorsal contact on the electrode.
Monitor ongoing safety and performance of the CORCYM heart valve devices and accessories for aortic, mitral and tricuspid valvular diseases in a real-world setting.
Primary objective: to investigate MPA exposure in a variety of autoimmune diseases in stable treated patients. Secondary objective: to develop predictive exposure models and evaluate the influence of population covariables on pharmacokinetics .The…
The objective of this study is to assess the efficacy and cost-effectiveness of a treatment strategy starting with surgical intervention compared to a starting treatment with steroid injection.