18 results
The objectives of this study are to gain new insights on [1] the cause of a higher clopidogrel resistance in DMII patients[2] the increased production of tissue factor in monocytes in DMII patients
This study will investigate the relationship between autonomic nervous system function and pain in fibromyalgia, with a specific emphasis on awareness of bodily sensations, also refered to as interoceptive awareness, as a potential modulator of pain…
Is there an association between involvement in incidents with airway irritants and respiratory effects in first responders.
The aim of the extended follow-up of the PIAMA cohort is: To investigate changes during the ages of 8 to 11-12 years in lifestyle, nutrition, physical activity and health related attitude and behavior that are relevant to the development of asthma,…
The aim of the project is to investigate the effects of five contrasting air pollution scenarios on respiratory and cardiovascular health of young healthy volunteers.
The objective of the present study is the evaluation of ventricular function in patients with congenital heart defects by means of newly developed echocardiographic techniques as tissue doppler and speckle traking stran rate echocardiography. Since…
The objective of the study is to establish biomarkers of human ageing.
This study will investigate whether odors can be conditioned to fearful events and themselves elicit fear in humans. Fear conditioning will be tested on two odors: a pleasant odor and an unpleasant odor. The research questions are 1) can odors be…
Primary:1. Which outcome variables of oculomotor performance and eye-hand coordinatio are useful to distinguish between Dementia with Lewy bodies, Alzheimerdementia and Parkinsondementia.Secundary:1. What are the base line values for the parameters…
Investigate the role of CD8+ T cells in AD by:a. Isolation of T cells from the skin and determination of the percentage and phenotype of CD8+ T cells in both acute and chronic AD, using the APT as an in vivo induction model. Comparison with…
The current study assesses activation of hippocampus and prefrontal cortex during sleep spindles in veterans with and without PTSD. Furthermore, the correlation between sleep spindles and memory consolidation will be examined.
To determine incidence, aetiology and course of gastroenteritis in case of hospitalisation with gastroenteritis. To gain insight in pathogen-specific duration, seriousness of the disease (including complications), and mortality. To investigate…
Studie A:1. To study the psychometric properties of the Dutch version of the PIQ in a non-clinical and clinical sample.2. to study the relationship of persecutory delusions and aggression in a non-clinical and clinical sample.Studie B:3. To test the…
To evaluate the correlation between the findings from the explained non invasive vascular tools (CIMT, PWV, FMD and OPS imaging) with prevalent CVD in diabetic individuals.To evaluate the potential of non invasive vascular tools for identification…
Immune regulation in Common Variable Immunodeficiency: the role of apoptosis and regulatory T cells.
To gain insight in the regulation of immune responses in patients with CVID
The objective of the study is to gain new insights in the causes of a higher clopidogrel resistence in type II diabetes mellitus patients
Our primary objective is to investigate the role of connective tissue growth factor (CTGF, a downstream mediator of profibrotic TGF-β1 activity) in peritoneal fibrosis and EPS. We hypothesize that soluble levels of CTGF and CTGF expression in the…
Primary objective:To demonstrate elevated numbers of CEC in clinically symptomatic patients with severe preeclampsia.Secondary objectives:- To analyze the relation of CEC levels with organ damage and dysfunction. - To analyze the relation of CEC…