65 results
1. To assess reference values of a pre-defined set of biomarkers for AKI in *surgical* infants with normal kidney function.2. To determine the incidence of AKI in critically ill infants, according to pRIFLE criteria.3. To evaluate the sensitivity…
Aim of this study is to confirm the results from ex vivo research in humans in a clinical setting. The objective is to perform optical spectroscopy measurements during surgical procedures in vivo, involving resection of either breast, liver or lung…
Hypothesis: Fiducial markers implanted in mediastinal lymph nodes by EUS-FNA or EBUS will show inter and intra-fraction lymph node position variability on 4D-(CB) CT-scansObjective: To quantify respiratory induced mediastinal lymph node motion and…
The main objective of the study is to monitor the factors effecting success of PDT, namely oxygen, photosensitizer concentration and, light dose before and during illumination to gather data that can be clinically correlated and later implemented.
This study concerns a research that is aimed to investigate the prevalence of the metabolic syndrome in a group of patients known with ANCA-associated vaculitis. Hereby we will compare the presence of the metabolic syndrome between an ANCA-…
In our recent studies we found indications of the existence of particular cognitive deficits as well as memory impairments following different regiments of cytostatic agents. Together with the indications form our animal studies of a potential…
This investigation aims to test a new, better and faster method voor measurement of the LVEF, that does not depend on technetium. The method relies on the tracer Gallium-citrate, a well-known molecule that is available in unlimited quantities in-…
The study aims (1) to determine the feasibility of Perfusion-PET with Gallium-68-citrate, prior to and during radiotherapy, and (2) to better understand the process of vascular response of tumor to radiotherapy, including differences between MLS and…
-Determination of the effects of an exercise program on ectopic fat accumulation in heart, liver and skeletal muscle-To assess the relationship between metabolic and inflammatory parameters with changes in MRI outcome-To assess the differences in…
Two key questions remain to be answered to further elucidate the mechanism of action: 1) is the effect on glucose metabolism dose dependent in Type 2 diabetes patients? and 2) Does UAG decrease glucose concentrations during an oral glucose loadThis…
Collecting T cells of 2 stage IV melanoma patients via leucapheresis for conducting test runs in order to develop a gene therapy study.
The aim of this study is to design and test new intervention therapies on tumorcells or tumorsamples on there sensitivity for several new drugs. Last few years there are a lot of new drugs available for cancer and have to be tested on there…
Comparison of the accuracy of achieved correction of the mechanical axis in the frontal plane relative to preoperative planning, endeavouring to achieve an overcorrection of a varus malalignment to 3-4° of valgus, comparing open and closed HTO*s.
To compare the palliative efficacy of talc pleurodesis with the indwelling catheter
Primary: • To determine the safety and feasibility of PK guided dosing of sunitinib Secondary:• To determine the objective response rate (according RECIST 1.1)• To determine the time to tumor progression and progression free survival• To validate…
The primary aim of this pilot-study is to determine the sensitivity of a new ambulatory method for measuring differences in mobility between before and after an intervention program. A secondary objective is to determine the conditions for using the…
The project proposes to study 12-month victimization rates and risk factors among persons with severe mental illness (SMI). The results will be compared with a matched sample from the general population. Additionally, we will develop a preliminary…
The aim of our project is to develop a test that identifies FAP patients with a high risk to develop desmoids. In a recent study, a so-called wound-response gene expression signature was developed on the basis of serum stimulation of fibroblasts in…
This study will evaluate the efficacy of: a low intensity, home-based, self-management physical activity program, and a moderate intensity, structured, supervised exercise program, in maintaining or enhancing physical fitness (cardiorespiratory…
Main and long-term goal of this project is to gain more knowledge of the relationship between genome-wide genetic variation and the risk of breast cancer, in the context of a positive family history. This knowledge will improve individual risk…