58 results
EXPLICIT aims tot obtain better functional outcome by early intensive rehabilitation. Next to clinical tests to measure improvement in function, neuroplasticity is assessed by fMRI, TMS and haptic robots. The combination of clinical outcome measures…
The proposed project aims at implementing the available scientific knowledge for recommending biopsies or active treatment, respectively, at the individual level in Dutch urological practice. To this end we have developed an internet based decision…
The objectives of this study are to gain new insights on [1] the cause of a higher clopidogrel resistance in DMII patients[2] the increased production of tissue factor in monocytes in DMII patients
In this research project, we will investigate the feasibility of multi-unit microneurography for the research of human muscle mechanoreceptors. We will therefore answer the following questions:1) How hard is it to find and maintain an effective…
To show whether Active C disc prosthesis is more effective than anterior discectomy with or without interbody fusion 1 year after surgery. Moreover, the incidence of adjacent disc degeneration will be evaluated 5 years after surgery.
In this study we will try to replicate and extend the findings of Domes et al (2007) of oxytocin effects on *mind-reading* in two specific groups of participants; i.e. in a group of high-functioning individuals with autism, and a normal comparison…
This phase I study aims to define the MTD of the combination of cisplatin/hyperthermia/lapatinib, to confirm that the 2 agents combined with hyperthermia can be administered safely, and to recommend a dose for further clinical studies.
The current study seeks to explore the SDOCT potential in a large group of patients in a clinical setting, and to compare it to existing, standard techniques.
to evaluate the effects of GH versus withdrawal of GH, after final height is reached, on weight, body composition, psychosocial functioning, carbohydrate metabolism, circulating lipids, and respiratory function during transition period until the age…
This study will investigate the relationship between autonomic nervous system function and pain in fibromyalgia, with a specific emphasis on awareness of bodily sensations, also refered to as interoceptive awareness, as a potential modulator of pain…
The goal of this project is to investigate the clinical feasibility of the robotic MRI-guided implant system for the implementation of fiducial gold markers for position verification for external beam radiation (or Intensity Modulated Radiotherapy (…
Can mobile echocardiographic and pulmonary function measurements be performed adequately and patient-friendly within 24 hours after admission to hospital and before discharge in COPD patients aged 65 years or over with an exacerbation?
Evaluation of the effect of treatment with the Meniett in patients with unstable Menière*s disease.
Technical validation of HIV antibody detection in capillairy blood sampled with the Demecal set.
- To asses the safety and toxicity of peri-ablative sorafenib given in doses of either 200 mg or 400 mg twice daily.- To asses the effect of perioperative sorafenib on the RFA induced mobilization of endothelial progenitor cells and cytokines…
The aim of the present pilot study is to obtain insight in the attainability of a study investigating the effectiveness of NeuroCARE NFT in more than average stressed but otherwise healthy young adults, using the current design. The claims that…
Is there an association between involvement in incidents with airway irritants and respiratory effects in first responders.
The objective of this study is to determine whether the dichotomization in good and poor outcome by the composite scale, corresponds better with the parents' and doctor's opinion on the outcome than the PSOM. The composite scale willl be…
Primary:Assessment of the effect of preventive versus on demand nutritional advice and a nutritional supplement (a daily energy- and protein-rich evening snack) on weight loss of patients receiving standard antiviral therapy with PEG-interferon in…
Methodology (part A):(1) What is the intra-individual variation in refill? (2) Is the magnitude of the ultrafiltration rate of influence on refill? (3) Is the amount of the initial intended blood volume decline of influence on refill? Implementation…