25 results
The aim of this study is twofold: 1) to measure ROTEM profiles in patients at risk for DIC to determine cut off values of ROTEM corresponding to the currently used International Society for Thrombosis and Haemostasis (ISTH) DIC scores, as well as to…
To assess the following research questions: 1. Does the use of 3D virtual preoperative planning of surgery improve functional outcome as measured by Patient-Reported Outcome in comparison to conventional surgery (using conventional radiographs and/…
Primary Objective: to evaluate arterial or synovial 89Zr-Df-crefmirlimab uptake on PET/CT in patients with GCA or RASecondary objectives are:1. Assessment of the relationship between 89Zr-Df-crefmirlimab uptake and the presence of CD8 T cells in…
To evaluate the added value of nCLE-imaging to conventional bronchoscopic peripheral lung lesion analysis on the diagnostic yield.
Our primary objective is to determine how often and to what extent potentially pre-malignant oral fields extend beyond their visible lesion. If those "underestimated" lesions have a greater chance to recur, narrow band imaging-guided…
The aim of this study is to investigate potential differences in blood flow patterns, wall shear stress and energy loss in patients after mitral valve repair with the resect and respect approach.
The current study*s primary aim is to test how trauma-focused therapy affects PTSD symptom-specific neural activity, and investigate neural markers that may predict treatment response to trauma-focused exposure. Furthermore, it is expected that…
To determine the clinical effectiveness of adjuvant therapy given to all unstaged (no lymph node dissection) high risk stage 1 endometrial cancer, compared with only node positive (staged) cases as judged by fulllymph node dissection.
Zie pagina 14 research protocol
The current study aims to elucidate neural correlates of pain processing and dissociative analgesia in PTSD. To this end, we want to replicate the pilot study by Mickleborough et al., (2011) and test the functional pain processing protocol with…
To investigate the accuracy and effectivity of a short non-invasive fluid-sensitive MRI to identify clinical arthritis in patients with recent onset hand(s) complaints.The purpose of the *amendment* is to investigate in patients with joint…
Primary Objective: The primary objective of this study is to map cerebral glucose metabolism of patients diagnosed with FBSS in an effort to elucidate imaging biomarkers that could predict the effectiveness of SCS treatment. Secondary Objectives:…
Primary objective: -To assess the predictive value of post-PCI RFR (resting full-cycle ratio) and FFR (fractional flow reserve) with regard to SSR (suboptimal stent result) in CTO (chronic total occlusion) patients. Secondary objectives:- To assess…
The study is intended to determine the performance of a QuantiFERON SARS-CoV-2 test that QIAGEN will bring to the diagnostic market. The proposed study will contribute to establishing the diagnostic parameters such as specificity, sensitivity and…
To determine markers related to early ageing and senescence in AYA cancer patients before and after systemic therapy, in order to assess treatment-related early vascular ageing and associated tumour and patient characteristics.
The primary aim of this research is to test the psychometric qualities of the Dutch translation of the CAI-NL. The secondary aim of the study is to evaluate the clinical value of the CAI-NL as an instrument in the treatment of people with severe…
1. To report the natural history of retinal degenaration in patients with biallelic mutations in the PCDH15 gene.2. To identify sensitive structural and functional outcome measures to use for future multicenter clinical trials in PCDH15-related…
The aim of this study is to validate the accuracy of SNNS for the detection of tumor-positive LNs using lymphoscintigraphy with radioactive tracer and NIR with ICG in patients with early EAC with regional LN involvement (clinically staged as T1N1).
Primary: To explore the diagnostic value to distinguish PAF and MSA of a variety of tests: corneal confocal microscopy optical coherence tomography (OCT) to measure the retinal nerve fibre layer thickness and total macular volume, corneal…
Our overall aim is to study how different pathological mechanisms in cerebral SVD influence WMH shape.Primary objectiveTo study the association of a more complex WMH shape with abnormalities in small vessel morphology.Secondary objectiveTo study the…