28 results
Benign liver tumors and cysts carry a significant burden on the quality of life in some cases. Apart from impairing symptoms, psychological burden might provide sufficient ground for surgical intervention. There is a variable approach to them…
The primary objective of this study is to identify biomarker fingerprints in patients with ulcerative colitis (UC) and Crohn*s disease (CD, that can indicate that an exacerbation has begun, although the patient still feels well. Ultimately, the…
The main objective of this study is to assess effectiveness of the COVID-19 vaccinations, based on humoral (anti-coronavirus antibody) immunity, in GCA and PMR patients. Other objectives are assessing antigen-specific cellular (T-cell) immune…
Primary objective: -To assess the predictive value of post-PCI RFR (resting full-cycle ratio) and FFR (fractional flow reserve) with regard to SSR (suboptimal stent result) in CTO (chronic total occlusion) patients. Secondary objectives:- To assess…
The study is intended to determine the performance of a QuantiFERON SARS-CoV-2 test that QIAGEN will bring to the diagnostic market. The proposed study will contribute to establishing the diagnostic parameters such as specificity, sensitivity and…
Objective: To investigate the adipose tissue response upon ex vivo SARS-CoV-2 infection, more specifically to answer the following questions:1. Is adipose tissue permissive to direct SARS-CoV-2 infection? 2. Are adipose tissue-derived factors…
The current study*s primary aim is to test how trauma-focused therapy affects PTSD symptom-specific neural activity, and investigate neural markers that may predict treatment response to trauma-focused exposure. Furthermore, it is expected that…
This study investigates Early Maladaptive Schemas (EMS) and modes in function of eating disorder subtype and behaviour, such as vomiting, laxative misuse, restricting, frequency of binges and BMI.
To compare safety and efficacy of EVOLUT R/Pro vs. SAPIEN3 Ultra for the treatment of a failing surgical aortic bioprosthesis
Primary Objective: To identify immune changes between baseline, one week of radiotherapy, end of radiotherapy and three months of durvalumab- Identification of differentially expressed proteins at all time points- Identification of differentially…
To report on the long-term effect modification by age of MPH treatment on brain structure and function, and clinical outcome, as measured by MRI scans, neuropsychological assessment, actigraphy and questionnaires, and to compare these results with…
The primary aim of this research is to test the psychometric qualities of the Dutch translation of the CAI-NL. The secondary aim of the study is to evaluate the clinical value of the CAI-NL as an instrument in the treatment of people with severe…
To determine markers related to early ageing and senescence in AYA cancer patients before and after systemic therapy, in order to assess treatment-related early vascular ageing and associated tumour and patient characteristics.
The primary objective is to evaluate the feasibility and adherence of 6 weeks of rehabilitation with the SEA in participants who underwent TL. The secondary objective is to examine if the SEA is an effective tool to improve swallowing function and…
To define the optimum laparoscopic hiatus hernia repair, ensuring long-term effect with minimal postoperative side effects.
The purpose of this study is to compare short-term postoperative recovery following THA between patients operated via the direct anterior approach and the posterior approach, using patient-reported and objective performance-based outcome measures.
The objective of this study is to evaluate the efficacy and safety of the PRIMA System in patients with atrophic AMD. Eligible subjects will be implanted with the PRIMA Implant. The subjects will be assessed with various visual function and…
Primary Objective:To establish the efficacy of treatment with Bimuno on total IBS symptom severity in patients with IBSSecondary Objectives:To assess efficacy of treatment with Bimuno on (I) abdominal pain, (II) bloating, (III) global IBS…
Primary objective:To investigate whether there are differences in DV flow measured during the 13-week GUO between pregnancies complicated by UPI and pregnancies not complicated by UPI.Secondary objectives:(1) To investigate whether there are…
To investigate whether daily electrical stimulation of gluteal and hamstring muscles combined with usual care is more effective than only usual in individuals with chronic SCI who often have PU*s and/or are at high of recurring PU*s regarding: 1)…