30 results
To investigate the effect of banded sleeve gastrectomy
The aim is to investigate the effect of a multimodal prehabilitation and rehabilitation program in frail patients of 70 years or older, undergoing elective surgery for non-metastatic CRC on1. One-year mortality 2. Postoperative complications,…
The goal of this study is to directly compare effectiveness of the Captain Morgan technique to the Allis technique in reduction of posterior dislocation of a THP using procedural sedation and analgesia (PSA) in the ER.
The aim of the proposed study is to define optimal treatment for the Lisfranc fracture dislocation, either primary arthrodesis or open reduction and internal fixation, in regard to quality of life, complications, functional outcomes and cost…
The aim of this study is to investigate non-inferiority of rituximab SC 336 mg to rituximab IV 200 mg.
The primary objective of this study is to investigate whether usual care combined with CBT improves QoL in patients undergoing surgery for endometriosis compared to usual care only. Secondary objectives are to investigate whether pain intensity,…
This study has been transitioned to CTIS with ID 2024-512968-57-00 check the CTIS register for the current data. The primary objective of the study is to assess the safety and feasibility of autologous salivary gland stem cell transplantation of the…
We will evaluate the clinical and cost-effectiveness of the two guideline recommended treatments for patients with persisting shoulder pain over a 12 month time period. Patients will be randomized to a local corticosteroid injection or referral for…
This study has been transitioned to CTIS with ID 2023-507303-55-00 check the CTIS register for the current data. To assess the effect of donanemab versus placebo on clinical progression in participants with early symptomatic AD with demonstrated…
The main objective of the proposed study is to evaluate if the Balanseat (used as intended) is feasible when only minor involvement from a therapist is required, contributes to therapy adherence and improves gait and balance compared to usual daily…
To evaluate whether Telisotuzumab Vedotin improves response rate and survival in participants who are c-Met+ with NSCLC. For the additional monotherapy cohort :Primary objective is to evaluate the safety and tolerability of telisotuzumab vedotin…
The objective of this trial is to evaluate safety and tolerability of an experimental drug, EO2401, in combination with another immunological treatment, nivolumab, in patients with advanced or metastatic ACC and progressive MPP.
This study has been transitioned to CTIS with ID 2024-510620-39-00 check the CTIS register for the current data. To compare belzutifan+lenvatinib to cabozantinib with respect to PFS per Response Criteria in Solid Tumors (RECIST) 1.1 as assessedby…
The goals of this study are to evaluate the union rate, patient satisfaction and functional results of the Anser Clavicle Pin in a larger cohort then approved in the study, Anser; A novel intramedullary device for fixation of midshaft clavicle…
This study has been transitioned to CTIS with ID 2023-510309-16-00 check the CTIS register for the current data. The primary objective to demonstrate that in CNOpatients with pain 3-monthly treatment with pamidronate will result in significant…
The primary study objective is long-term safety of RGX-501 and secondarily evaluation of the long-term effects of RGX-501 on LDL-C and other lipid parameters.
Our goal is to investigate the effect of EMDR treatment on abdominal pain in patiënts with Irritable Bowel Syndrome. In addition we will investigate the effect of EMDR treatment on other IBS physical complaints and on patients' experienced…
The aim of this study is to evaluate the feasibility and safety of new esophageal preserving treatment algorithm for patients with high-risk T1a or T1b EAC consisting of radical ER of the tumor, followed by a SNNS procedure with selective…
To determine the effect of salt (NaCl) supplementation on (1) physiological parameters (such as serum potassium) and on (2) clinical signs and symptoms and quality of life.
This study aims to investigate the effectiveness of EMDR (n=32) in comparison to a waiting list in (n=32) adolescents (12-18 years) with a primary diagnosis of MDD (DSM-5; American Psychiatric Association, 2013). It is hypothesized that the…