91 results
1. To identify and specify bacteria by using RT-PCR on blood and cerebrospinal fluid (CSF) in preterm infants, having nosocomial sepsis and meningitis.2. To compare RT-PCR (see aim 1) with the gold standard bacterial culture in preterm infants,…
Aim of this prospective study is to determine (temporal changes in) the intestinal microbiota in faecal specimens and microbiota adhering to the intestinal mucosa using bacterial DNA-based profiling methods.
In 2009, a new combination of MRI sequences was published by Deoni et al. (2009) that promised the ability to measure the myelin water in vivo over the whole head in a clinically useful time. Referred to as mcDespot (multi-component driven…
The focus of this study is to get more insight in the pathophysiology of IUGR. The main goal is to investigate the applicability of STIC in determining fetal cardiac function in IUGR.
The key objectives of this study are:1. To determine by means of IENFD whether the PNS is involved in patients with autonomic complaints in MS. The obtained IENFD values will be compared with the age and gender matched healthy normative data,…
1. To evaluate the clinical usefulness of STIC with post-process rendering capability. Our goal is to investigate whether STIC gives more accurate information about a suspected cardiac anomaly, compared to conventional 2D ultracardiography.2. To…
We will investigate the feasibility of using STIC technology to evaluate the normal fetal cardiac anatomy and morphology in different stages of gestation. Further we aim at making normograms of different intracardiac parameters in relation to…
The primary objective is to investigate the influence of auditory and non-auditory factors on speech recognition abilities in quiet and in noise in CI users. For this reason we will study the effects of linguistic skills and working memory capacity…
The main goal of the proposed experiment is to provide evidence for the hypothesis that the adaptation range of posture control behaviour with only proprioceptive feedback is similar to the adaptation range with visual and tactile feedback also…
Assessment of the effect of kidney-pancreas transplantation in diabetic nephropathy patients on microvascular alterations using orthogonal spectral polarization and correlate this effect with markers for endothelial cell dysfunction and fibrosis
Assessment of microvascular alterations using orthogonal spectral polarization and correlate this with markers for endothelial cell dysfunction, fibrosis and histology in patients with renal function impairment who will undergo renal biopsy and…
The primary goal of the study is the prevalence of NRH in patients with IBD, who have been treated for at least five years with azathioprin or 6-mercaptopurin. A MRI of the liver, using the Seiderer protocol, and a percutaneous liver biopsy will be…
Aim of the study is to develop an intraoperative technique for SLN mapping in colon cancer which is suitably in daily practice in colon surgery in an average hospital setting.
Primary objective: To study the faesibility of SLNM in patients with histological proven colon cancer using NIR-laparoscopy.Secondary objectives: To study the incidence of micrometastasis with the use of ICG and RT-PCRTo determine the number of…
Are changes in cognitive functioning related to structural changes in the brain in patients with type 1 diabetes mellitus. How are these changes related to diabetic complications like duration of chronic hypoglycaemia, disease duration and presence…
The main objective of this study is to increase current insights into the role of auditory and cognitive factors in the reduced ability to understand speech in noisy environment, particularly for hearing impaired people. These insights will help to…
Applicability of fetal brain imaging techniques for clinical purposes.
We aim to observe in whole blood at patients core temperature and normotemperature how mild therapeutic hypothermia affects coagulation and in particular fibrinogen, in post cardiac arrest patients.
To assess the prevalence of BHD among patients with spontaneous sporadic and familial pneumothorax.
Feasibility of PET probe guided extirpation of FDG-PET positive lymph nodes which are negative on other imaging modalities in head and neck cancer patients scheduled for primary irradiation.