4 results
This study aims to isolate and culture myogenic stem cells called mesoangioblasts from the muscle biopsies to explore if genetic correction of LAMA2 mutations using CRISPR-Cas9 can be achieved and subsequently assess the effect in vitro, as a first…
1. To either confirm or refute the hypothesis that a subset of brain regulatory T cells exists in humans and expands after stroke.2. To identify immunological biomarkers that can be used in stroke clinical trials targeting the adaptive immune system…
The primary objective is to assess the role of obstructive sleep apnea related pathophysiological mechanisms in the initiation of atrial fibrillation by a multi-parametric strategy that combines the estimated parameters. The main hypothesis is that…
To examine the PVS domain, and in particular reward circuits and behaviour, in large genetically informative cohorts comprising 500 individuals (including 125 SCZ patients, 125 BP patients, 125 relatives and 125 controls) already ascertained in the…