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Senescence and the early ageing phenotype after chemotherapy for testicular cancer: the SEA-CAT study

The aim of this study is to improve our understanding of the development of late effects after cancer treatment and reveal potential targets for intervention/prevention. Therefore we will investigate mechanisms behind the early ageing phenotype…

Prediction of Post-induction Hypotension with Arterial Pulse wave applied Machine Learning, a non-randomized prospective data collection observational study.

Primary Objective:The primary aim of this study is data collection of continuous noninvasive arterial pressure waveform signals with the ClearSight (CS) finger cuff, continuous invasive arterial pressure waveform signals when an arterial cannula is…

An Open Label Extension Study of Voxelotor (GBT440) Administered Orally to Participants with Sickle Cell Disease Who Have Participated in Voxelotor Clinical Trials

The objective of this open-label extension (OLE) study is to assess the effect of long-term safety and treatment effect of Voxelotor in participants who have completed treatment in Study GBT440-031, using the following parameters:- Safety based upon…

Influence of posterior vitreous detachment on retinal detachment after
lens surgery in myopic eyes

The aim of the study is to document the presence and/or post-operative development of PVD and to assess its influence on the incidence of PRD in myopic patients in a time period of three and five years after lens surgery.