299 results
To improve the response rate to treatment of severe acute GVHD (grade II-IV with gut involvement ) by adding infusion of Mesenchymal Stroma Cells to standard high dose prednisolone.
To assess the effect of amitriptyline on gastro-esophageal symptom severity and on esophageal sensitivity to acid perfusion and balloon distension in patients with documented functional heartburn.
To determine prospectively the correlation between in vitro patient-derived organoid response and progression-free survival.
To determine whether guided growth of the proximal femur decreases the risk of further hip migration and need for further surgery in cerebral palsy patients.
To evaluate the effect of transcutaneous electrical nerve stimulation (TENS) in patients with ANOCA on the change in the summary score of the Seattle Angina Questionnaire (SS SAQ) after 1 month treatment with TENS, compared to baseline.
This study examines a the role of four key ultra-high-risk criteria for personality disorders: interpersonal trauma, personality functioning, quality of social support system and subclinical features of borderline personality disorder. For two of…
This study aims to evaluate the Corsano Cardiowatch 287-2 for heart rate, heart rate variability (RR intervals), oxygen saturation, respiratory rate, and blood pressure during strenuous activities such as High-Intensity Interval Training (HIIT).…
The aim of this study is to evaluate the validity of various algorithms for gait bout detection and spatiotemporal measures with a 3-IMU based sensor set worn on the feet and lower back. If this algorithm can be validated, it can be used to obtain…
This study will initially focus on gaining insight into the difference between the current set PEEP level following cardiothoracic surgery compared to individually adjusting the PEEP level using EIT or Pes.
2 OBJECTIVES2.1 Primary Objective: To address the existing knowledge gaps and advance our understanding of cognitive variability, the CODEC study aims to integrate experience sampling methods, longitudinal designs, deep phenotyping cohorts, and…
The aim of this study is to evaluate if a PPT can significantly decrease - or possibly prevent - the collapse of the trachea in newborns with EA and moderate or severe TM. Additionally, the study aims to determine whether the observed effect of PPT…
To identify clinical and immunological parameters that predict the course of disease of non-tuberculous mycobacterial skin and soft tissue infections.
The objective of this study is to collect data on treatment outcomes when treating mCRPC using Lu-PSMA. In addition to this, the study aims to identify correlations between biomarkers (ctDNA and CTC*s) and dosimetry data with treatment outcomes of…
To improve survival and qualitity of life in patients with LAPC using ablative treatment with MRgRT (5x10Gy) in addition to standard of care.
Primary Objective: To assess the effectiveness of a personalized executive functioning training program for 4-6 year old children with severe CHD.Secondary objectives: - To relate training effectiveness to disease and treatment characteristics and…
Do the T-REX Twente precautions have a positive impact on the quality of life (MAcNew QLMI), level of physical activity, and reduction of fear of movement in heart patients after a total median sternotomy compared to the (current) standard…
Primary Objective: • To investigate the feasibility of utilizing PAI as a means of detecting the SLN in patients with melanoma or breast cancerSecondary Objective(s): • Determine the most effective wavelengths for detecting ICG in PAI• Investigate…
The aims of this project are to 1) to determine the non-inferiority of inter-CBT, compared to a benchmark study where CBT was provided by psychologists (TIRED study), in its effect on reduction in cancer-related fatigue, 2) to adapt CBT delivery to…
The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve DMS system to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main…
This research aims to examine the feasibility of home monitoring of serum uric acid for both patients and stakeholders, using a digital home measuring device in conjunction with a nurse-led T2T approach.Primary research question:What is the…