65 results
We hypothesise that glaucoma patients with non-overlapping visual field defects have poorer binocular visual performance while performing complex visual tasks than would be predicted from their visual field. Knowledge on this topic is highly…
To compare the effect of radioactive Iodine or hemithyroidectomy on the symptoms and quality of life (QoL) of patients with a benign euthyroid goiter.
Primary objective is to investigate the effectiveness of ADAPT vs TAU on family functioning of veteran families as reported by the veteran. Secondary objective is to investigate the effectiveness of ADAPT versus TAU on family functioning as reported…
This study investigates the impact of a goal directed nutritional support protocol on sarcopenia in oncological patients undergoing an esophagectomy and secondary the incidence of anastomotic leakage and pneumonia, surgical infection and lenght of…
The primary objective of this study is to optimize the ultrafast ultrasound flow imaging technique for intra and extra cardiac flow visualization in neonates. The secondary objectives are 1) to compare cardiac output determined using conventional…
1) To investigate the effectiveness of Multi-family therapy (MFT) versus individual oriented treatment as usual (TAU) on end-of-treatment family functioning of veteran families, as reported by the veteran. TAU consists of supportive counselling or…
To determine if SSA are effective in decreasing transfusion requirements and improving quality of life while being cost-effective.
A multicenter randomized placebo controlled treatment study of leflunomide in polymyalgia rheumatica
This study has been transitioned to CTIS with ID 2024-514210-12-00 check the CTIS register for the current data. To investigate whether the use of leflunomide can prevent relapses during glucocorticoid tapering in patients with polymyalgia…
The aim of the study is to gain insight, based on 30 N=1 trials, into whether intensive ESM monitoring can be used to evaluate the consequences of dose reduction of antipsychotic medication by detecting meaningful within-subject changes in daily…
The primary aim is to validate the finding that addition of physiological doses of hydrocortisone reduces dexamethasone-induced clinically relevant neurobehavioral problems. The secondary aims are to study the role of genetic variation, psychosocial…
Primary objective: The primary objective of this non-randomized intervention trial is to investigate whether TAVR improves exercise capacity in patients with preserved LVEF and NF/LG or LF/LG severe AS reclassified based on hybrid CT/TTE-derived…
The objective of this study is to determine whether contralesional cTBS treatment modulates the interhemispheric imbalance in excitability or local or transcallosal inhibitory processes in the motor network of a population of stroke patients…
To assess the effectivity and feasibility of HCV RNA self-testing in reducing the time to diagnosis of HCV re-infection in MSM previously cured of an HCV infection, compared to the current diagnostic standard of care. To evaluate whether the uptake…
Primary objectives• To identify the percentage of patients in which a drug resistant clone can be detected with ctDNA before the emergence of radiological progression.• To determine the success rate of crizotinib and osimertinib combination…
Main objective:1. To estimate the Overall Response Rate (ORR) and the clinical benefit rate in selected cohorts of patients with hematologic malignancies,separately for each cohort2. To evaluate the safety of the selected dose regimes in an expanded…
The aim of this study is to improve our understanding of the development of late effects after cancer treatment and reveal potential targets for intervention/prevention. Therefore we will investigate mechanisms behind the early ageing phenotype…
Primary Objectives: - To evaluate the safety in mother and neonate/infant of nipocalimab administered to pregnant women at high risk for EOS-HDFN. - To evaluate the efficacy of nipocalimab as measured by proportion of patients with live birth at or…
The primary objective of this study is to explore the diagnostic accuracy of MRDTI in the diagnostic management of acute and chronic SVT in a prospective diagnostic proof of concept study. The secondary objectives include optimizing MRDTI sequences…
The objective of this study is to describe cognitive profile and dimensions of psychopathology in subjects with CNV disorders.
The primary objective of this trial is to evaluate quality of life outcomes in patients with CRLM during a patient-controlled follow-up approach. Secondary objectives are to evaluate anxiety, fear of cancer recurrence, survival, and the cost-…