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Goal directed fluid removal with furosemide in intensive care patients with fluid overload - A randomised, blinded, placebo-controlled trial

This study has been transitioned to CTIS with ID 2024-512186-14-00 check the CTIS register for the current data. To assess benefits and harms of goal directed fluid removal with furosemide versus placebo on patient-important outcome measures in…

The effect of low-dose rhythmic 17-β-estradiol administration on bone turnover in postmenopausal women

To investigate the effect of low-dose rhythmic transdermal 17-β-estradiol on serum P1NP (marker of bone formation) and CTX (marker for bone resorption), versus continuous low-dose and standard-dose continuous transdermal 17-β-estradiol…

Multiple Sclerosis treatment with Autologous Hematopoietic Stem Cell Transplantation (MS-ACT): A long-term prospective observational study in the Netherlands

To perform long-term pre-specified follow-up of patients undergoing aHSCT for refractory RRMS.

Body Weight Adjusted Clopidogrel treatment in patients with CORonary artery Disease (BW-ACCORD)

This study has been transitioned to CTIS with ID 2024-518890-33-00 check the CTIS register for the current data. To determine if clopidogrel treatment can be optimized in patients with a low or high BW/BMI compared to patients with a normal BW by…

The effects of rituximab and obinutuzumab on lymphocyte subsets in peripheral blood and lymphoid tissues of SLE patients

This study has been transitioned to CTIS with ID 2024-518965-85-00 check the CTIS register for the current data. The primary objective of this study is to investigate the potential differential effects of RTX and OBI on the composition of lymph…