57 results
To determine if 6 days of antibiotics has equal efficacy compared to 12 days for patients hospitalized with cellulitis.
This study has been transitioned to CTIS with ID 2024-518684-35-00 check the CTIS register for the current data. The current project proposal continues on our findings of the performed prospective cohort study, aiming to develop a biomarker guided…
In an effort to collect safety and effectiveness information on the stent, Medlogics is conducting the Cobra II study.
The primary objective of this study is to investigate whether pregabalin at a dose of 150-600 mg twice a day reduces pain in patients with chronic neuropathic pain after herniorraphy. This research question will be answered by testing of the…
Primary Objective:The primary objective of this study is to demonstrate the long-term (3 years) favorable visual acuity and adverse event outcomes for the Clareon IOL compared to historical SPE rates as reported in EN ISO 11979-7:2014.Secondary…
The primary objective of this trial is to study the effect of the moderate CYP3A4 inhibitor erythromycin on the pharmacokinetics of palbociclib, measured as AUC0-24h, Cmax and Cmin.The secondary objective of this trial is to compare the incidence…
The primary objective of this study is to describe the pharmacokinetic profile of total and unbound plasma concentrations of ropivacaine, when used for LIA in TKA surgery without tourniquet.
To examine the effect of two different degludec dose adjustments on glucose profiles and the incidence of (nocturnal) hypoglycaemia after oxidative exercise in people with DM1 at elevated risk of hypoglycaemia.
This study will evaluate how safe administering obinutuzumab as a short duration infusion (SDI) during cycle 2 and from cycle 2 onwards in combination with chemotherapy in patients with previously untreated advanced FL is.
To evaluate the effect of 12 weeks subcutaneous evolocumab (140 mg pre-filled pen every 2 weeks) compared to placebo on post fat load non-HDL-C levels in 30 subjects with FD, in a multicenter, randomized, placebo-controlled, double-blind, crossover…
This study has been transitioned to CTIS with ID 2024-514183-21-00 check the CTIS register for the current data. The primary objective of this trial is to determine whether, in subjects with moderately to severely active UC, treating to achieve a…
This study has been transitioned to CTIS with ID 2024-518101-18-02 check the CTIS register for the current data. The main objective of this project is to associate the gut microbial community with treatment efficacy (i.e., relieve in symptoms and…
This study has been transitioned to CTIS with ID 2024-511743-26-00 check the CTIS register for the current data. Primary Objective: Major amputation rate after 12-months of follow-upSecondary Objectives: - Amputation-free survival- Health-related…
This study has been transitioned to CTIS with ID 2024-512602-26-00 check the CTIS register for the current data. Evaluate the (cost-) effectiveness of ulipristal in comparison with standard surgical treatment for symptomatic uterine fibroids,…
This study has been transitioned to CTIS with ID 2024-519078-38-00 check the CTIS register for the current data. 1) To evaluate the efficacy and safety of the standard clinical care at the AMC in this patient population by the clinical outcomes (…
This study has been transitioned to CTIS with ID 2024-514055-15-00 check the CTIS register for the current data. Primary: • Investigate the effectiveness and tolerability of methotrexate as first-line therapy in patients with pulmonary sarcoidosis…
The objective of this study is to demonstrate the superiority of Distal Transradial Access (DTRA) to Conventional Transradial Access (CTRA) regarding forearm radial artery occlusion (RAO) using the 6Fr Glidesheath Slender (GSS).
This study has been transitioned to CTIS with ID 2024-511008-17-00 check the CTIS register for the current data. To assess whether lacosamide is as efficient in the treatment of chemotherapy-induced neuropathic pain as duloxetine
The objective of this study is to examine the effect of riluzole on the glutamate/GABA balance in the brain in patients with 22q11.2DS. The secondary objective is to examine the effects of riluzole on psychotic symptoms and cognitive functioning. In…
To assess the safety of the Orsiro Mission Stent System in subjects at high bleeding risk (HBR) undergoing PCI followed by 30-days Dual Antiplatelet Therapy (DAPT).