203 results
To validate MRI for assessing craniocaudal tumor extension with histopathology using non-rigid egistration. In addition to 3 Tesla magnetic resonance T2-weighted imaging, diffusion weighted imaging (DWI) and dynamic contrast enhanced (DCE) imaging…
- To systematically determine the influence of disease activity of RA on the metabolic syndrome of patients with chronic RA (disease duration > 2 years).
The primary objective of this study is to assess the outcome of taxane- based chemotherapy in ER-positive MBC HER2-negative patients with progression after receiving endocrine therapy (with at least an AI) who have an ESR1 mutation measured in…
Primary Objective• To characterize preliminary targeting properties of [68Ga]-NeoBOMB1 in patients with malignancies known to overexpress GRPR.Secondary objectives• To assess safety and tolerability of a single diagnostic dose of [68Ga]-NeoBOMB1…
To explore the possibility of NIR fluorescence intra-operative angiography of the meniscus using ICG in patients undergoing total knee arthroplasty
This study has been transitioned to CTIS with ID 2024-513538-40-02 check the CTIS register for the current data. To determine the value of quantitative whole body PET with [18F]PEG-Folate to predict development of clinical arthritis within one year…
Primary:To evaluate the superiority of a patient-centred, education based, clinical strategy to reduce the volume of endoscopies for dyspepsia in patients over 18 years of age without alarm symptoms, referred for OGD through open-access endoscopy…
The current pilot-study aims to validate Virtual Reality (VR) environments that elicit variance in virtual aggression and social information processing (SIP) and consist of the following research questions.1. Do children experience VR environments…
This study has been transitioned to CTIS with ID 2024-520392-27-00 check the CTIS register for the current data. The primary objective is to evaluate the difference in 68Ga-exendin tracer accumulation in the pancreas of women with and without a…
The objective of this study is to evaluate the acute effects of PEEP on the position, length, and contractibility of the diaphragm.
The primary objective of the entire study is to compare rogaratinib (BAY1163877) with chemotherapy (docetaxel, paclitaxel or vinflunine) in terms of prolonging the Overall survival (OS) of patients with FGFR positive urothelial carcinoma.
Primary Objective: To compare the efficacy of MEDI-551 versus placebo in reducing the risk of an NMO/NMOSD attack in subjects with NMO/NMOSD.Secondary Objectives:1. To compare the efficacy of MEDI-551 versus placebo on the reduction of EDSS…
2.1 HypothesisPrimary infection with Mtb induces temporal changes in the innate immune system, known trained innate (aangeboren) immunity, and the extent of trained innate immunity influences subsequent activation of adaptive (verworven) immunity.2.…
To compare the effects of various upper extremity positions on the sagittal spinal alignment, to determine which position corresponds the most with the neutral position and to determine which position is the most reliable across repeated…
To investigate the feasibility of the implementation of a point-of-care immunological test based on blood cells of all trauma patients with the aid of an automated load-and-go flow cytometer in an acute trauma care setting at the shock room.
Prospective, primarily direct comparison of 11C-methionine PET versus 11C-choline PET, and secondary 4D-CT, to explore what PET tracer to use and in which order to use the functional versus the anatomical imaging technique in the setting of primary…
The present study aims to:A) acquire a pharmacokinetic model of [18F]PSMA ([18F]-DCFPyl), by which simplified methods to quantify [18F]PSMA PET signal will be validated ; andB) assess the repeatability of those simplified quantitative method.
Main objective is to compare the incidence of subclavian vein thromboses after TLE by manual traction alone versus TLE with use of the mechanical rotational dilator sheath in case of fibrous adhesions hampering extraction by manual traction alone.…
The main study aim is the in vivo and ex vivo investigation of the expression and distribution of the GLP-1R in the pancreas of children (< 16 years) with proven endogenous congenital hyperinsulinism who qualify forsurgery based on response…
Primary objective:* To determine the protective efficacy of repeated short term exposure to hookworm infection Secondary objectives:1. To explore the immunological response after repeated hookworm infections2. To evaluate the safety of and number of…