164 results
To investigate whether statin treatment can prevent or delay the development of RA in persons at increased risk of RA.
To determine if 6 days of antibiotics has equal efficacy compared to 12 days for patients hospitalized with cellulitis.
The hypothesis is that using CPAP decreases the severity of the underlying mechanisms in sleep apnea patients.
To compare the effects on glycemic control, patient reported outcomes (PRO) and experiences (PRE) of rt-CGM with FGM in a real-life outpatient setting among persons with T1D.
To establish the test-retest reliability of the 13C-PBT for measuring Phe hydroxylation in patients with PKU.
This study has been transitioned to CTIS with ID 2024-517636-22-00 check the CTIS register for the current data. The main objective of the present study is to investigate the association between in vivo regional synaptic loss ([18F]SynVesT-1 PET),…
To test if a CRT-targeted resuscitation based on clinical hemodynamic phenotyping can improve a hierarchical clinical outcome - mortality, time to cessation of vital organ support, and length of hospital stay, all within 28 days - in septic shock…
Determine speech understanding in noise with the AB*s bimodal BF directional hearing technology.
This study has been transitioned to CTIS with ID 2024-518966-28-00 check the CTIS register for the current data. The primary goal of this study is to investigate the effects of belimumab on the composition of lymph nodes and the inflamed synovial…
The objectives of this study are: 1. to identify new genetic variants causing or predisposing to PD; 2. to characterize the clinical phenotype in PD associated to specific genetic variants; 3. to investigate the molecular mechanisms of PD in…
This study aims to determine the effect of nocturnal versus daytime cyclic infusion of parenteral nutrition in adult chronic intestinal failure patients on bone turnover, glucose metabolism, nitrogen balance, sleep and wake rhythm and clock genes…
Test whether a mindfulness-based cognitive therapy intervention (MBCT) improves psychological distress, clinical symptoms, slows neurodegeneration, and/or enhances neuroplasticity in PD.
This study has been transitioned to CTIS with ID 2024-518931-12-00 check the CTIS register for the current data. Primary:- To test whether bevacizumab added to a backbone chemotherapy regimen (temozolomide or irinotecan-temozolomide or topotecan-…
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The primary outcome parameter is the Gout Activity Score (GAS)after 6 months of rasburicase treatment. Secondary outcome parameters are the serum uric acid concentration, the clinical evaluation of tophus load, patient reported outcomes: MD-HAQ, GAQ…
Confirm the technical performance of the new IMPERIA Delivery System and evaluate the safety and efficacy of the entire ALLEGRA THV System.
1. Evaluate the relation between pretreatment muscle weaknesses, spasticity, abnormal synergies, and changes in viscoelastic joint properties on the one hand, and changes in upper extremity spasticity following treatment on the other hand in…
To determine the effects of the PCP+SM compared with usual care on BP control in adults with hypertension. To determine the effects of the PCP+SM compared with usual care on antihypertensive medication use in adults with hypertension. To determine…
The goal of this trial is to determine the efficacy of LC in patients with IAP in the prevention of recurrent acute pancreatitis and biliary events. The secondary goal of this trial is to assess the occurrence of biliary events, complications of LC…
To identify novel (causal) risk factors, including biomarkers and genetic determinants for disease progression and (severe) diabetes complications in people with T2D, in order to develop new, more targeted and effective therapies that will improve…