174 results
18-22 YEAR OLD MALES WIHT A NORMAL WEIGHTExamine the possible attenuating cardiometabolic health effects of (A) hourly, 10-min standing interruptions, when compared to a single bout of prolonged sitting, and (B) sitting on a stability ball, when…
The primary objective is investigating the effectiveness of *Mindlight* in treating (sub)clinical symptoms of anxiety in children who are diagnosed with an autism spectrum disorder. The secondary objective is to examine the factors that moderate and…
From p12 of C1 protocol document:To assess how diurnal rates of muscle protein synthesis are altered during a short-term (3-day) implementation of resistance exercise training when compared to normal daily activity.
In the current study, we will 1) evaluate the usefulness and reliability of this new device, and 2) evaluate whether the anatomic site used will impact the measured CPM effect.
We hypothesize that dietary supplementation with seaweed will improve glucose regulation in T2DM patients.
Recently, (changes in) the gut microbiome (flora / bacteria) have been associated with obesity and insulin resistance, and other cardiovascular risk factors or atherogenic processes. Venous thrombosis shares these risk factors, probably by a shared…
Aim of this study is to assess the effects of exercise intervention on breast cancer patients* quality of life on the short (6 months) and long-term (24 months) according to the cmRCT design and to test the utility of the cmRCT design in the field…
Investigating the progress of the self-esteem and well-being before, during and after the Dramatherapeutic Self-Image module in clients with a personality disorder who are in treament phase 1 of outpatient schema focused therapy.Investigating which…
2.1 HypothesisPrimary infection with Mtb induces temporal changes in the innate immune system, known trained innate (aangeboren) immunity, and the extent of trained innate immunity influences subsequent activation of adaptive (verworven) immunity.2.…
In this study, the agreement between liquid biopsy and tissue biopsy based KRAS/EGFR molecular diagnostics will be determined. Additionally, pairwise comparison of different liquid biopsy based molecular tests will be performed based on several…
In the specified patient groups, quantitative outcomes will be compared in both weight-bearing images and non-weight-bearing images. In detail, the location, displacement and rotation of individual bone fragments in the foot will be measured in 6…
To examine the effect of two different degludec dose adjustments on glucose profiles and the incidence of (nocturnal) hypoglycaemia after oxidative exercise in people with DM1 at elevated risk of hypoglycaemia.
- To investigate the baseline profile and inter- and intra-subject within-day and between-day variability of the fatty-acid profiles including fatty-acid desaturation index (FA-DI) and PUFAs in the plasma of patients with Parkinson*s disease and…
This study will evaluate how safe administering obinutuzumab as a short duration infusion (SDI) during cycle 2 and from cycle 2 onwards in combination with chemotherapy in patients with previously untreated advanced FL is.
* Part A: To investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of increasing doses of YTX-7739 in healthy subjects. * Part B: To study the effect of food on pharmacokinetics of YTX-7739 in a selection of subjects who…
To evaluate the effect of 12 weeks subcutaneous evolocumab (140 mg pre-filled pen every 2 weeks) compared to placebo on post fat load non-HDL-C levels in 30 subjects with FD, in a multicenter, randomized, placebo-controlled, double-blind, crossover…
This intervention study investigates the effectiveness, costs and cost-effectiveness of a protein-enriched diet and resistance exercise training for 3 months on bone and muscle health, and quality of life in older adults recovering from an acute hip…
Is to evaluate long-term safety of oral levosimendan in amyotrophic lateral sclerosis (ALS) patients.
Perioperative bleeding in the setting of noncardiac surgery is strongly associated with 30-day cardiovascular complications and mortality. Trial evidence suggests that intravenous TXA reduces perioperative bleeding and transfusion in orthopedic…
This Phase 2b/3 double-blind, placebo-controlled study will evaluate the safety, tolerability, and effects of livoletide on food-related behaviors in patients with Prader-Willi Syndrome (PWS).