13 results
In the proposed study, two main issues will be addressed: first, it will be studied whether a high dose (4.0 mg) of FA supplementation periconceptional has an added value over the now recommended low dose of 0.4 mg in the prevention of congenital…
The aim of this study is to assess the efficacy of Cryolijm SQ (Sanquin blood supply foundation, Groningen, The Netherlands) fibrin sealant in reducing postoperative drainage at the abdominal donor site which could result in earlier drain removal,…
This study is aimed at understanding status and future cardiovascular disease (CVD) risk in UC outpatients in remission undergoing different anti-inflammatory therapeutic regimens (tofacitinib (a JAK1 - inhibitor), anti-TNF (infliximab or adalimumab…
The effects of physical activity pattern on disease progression in patients with knee osteoarthritis
Primary Objective:• To determine the impact of different types and intensities of physical activities, i.e. running, cycling, tennis and hiking, on the structural progression of knee OA in a group of early-stage knee OA patients.Secondary Objectives…
The goal of this study is to evaluate the effectiveness of the serious game *Broodles* in improving the quality of life and psychosocial well-being of siblings (6-9 years) of children with VI and/or ID.
The purpose of this pilot trial is to determine whether it is feasible to conduct a full multicentre randomized controlled trial (RCT) to determine whether low-dose aspirin (ASA) is efficacious and safe at preventing postpartum venous…
To determine which patients, individually classified for VTE ánd bleeding risk, will benefit from prolonged anticoagulant treatment without being unnecessarily exposed to its risks.
The main objective for the current project is to investigate the effect of acute systemic inflammation - induced by LPS exposure - on energy metabolism, measured as resting metabolic rate (RMR), in apparently healthy volunteers.
Primary Objective: To conduct a randomized controlled trial (RCT) to investigate the effectiveness of an online intervention in reducing depressive symptoms (as measured by the simplified PHQ-9) in COPMI between ages 10 to 26 years old.Secondary…
The objective of the study is to assess the effect of music on postictal agitation when played peri-interventionally for patients undergoing electroconvulsive therapy for severe depression.
The objectives of this study are to (1) test the efficacy of sVRE versus CAU in 180 children undergoing surgery on the postoperative pain of the child (primary outcome), postoperative analgesics use, anxiety level of the child during induction of…
To investigate the effect of distracted consumption on glucose variability in women with GDM and to investigate moderating effects of type of distractor and perceived stress.
The primary objective of this trial is to study in a prospective randomized comparison whether a restrictive RBC transfusions strategy is non-inferior compared to a liberal strategy in patients on ECMO with respect to 90-day mortality.