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Post-market Clinical Follow-up Study to Provide Safety, Performance and Clinical Benefits Data of the Vanguard PS Open Box Porous Femoral (Implants and Instrumentation) - A Consecutive Series Study

The objective of this retrospective consecutive series PMCF study is to collect long-term data confirming safety, performance and clinical benefits of the Vanguard PS Open Box Porous Femoral (implants and instrumentation) when used for total knee…

The effectiveness of a diet with beef as key protein component versus a plant-based diet to support integrated muscle protein synthesis rates in healthy older individuals

To compare the effectiveness of a diet with beef as key protein source versus an isocaloric and isonitrogenous plant-based diet to stimulate integrated muscle protein synthesis rates over a 10 day period, in healthy older individuals, with and…

The effect of yoga on endocrine therapy induced musculoskeletal symptoms in women with breast cancer

The objective of the proposed study is to assess the effectiveness of a 4-month yoga program compared to a waiting list control group on musculoskeletal complaints in women with hormone-positive stage I-III breast cancer receiving endocrine…

Retrospective evaluation of surgically treated unstable type C ankle fractures: long term functional and radiological outcomes.

To evaluate the long term functional and radiological effects of surgical treatment of Weber type C (AO 44-C1/2/3) fibular fractures

Optimizing and Innovating Blended Interventions and Aftercare for Alcohol Addiction (OptiBlend): A Randomized Controlled Trial

Primary objective: In the RCT, we expect to find at least a small to medium (d>=.35) between-group effect between BL1 and BL2 compared to TAU. In the EMA, we expect to find at least a medium (d>=.6) between-group effect between the BL1…

Exploring the effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on the acute stress responses.

The primary aim of this study is to assess the efficacy of taVNS in mitigating the acute stress response induced by the Maastricht Acute Stress Task (MAST) among healthy subjects, measured by cortisol levels in saliva samples.Secondary objectives…

Scandinavian trial of Uncomplicated Aortic Dissection Therapy

Primary Objective: The primary objective of the study is to determine the superiority of TEVAR versus SMT in reducing the incidence of all-cause mortality. Secondary Objectives: The secondary objectives of the study are:• To compare the risk of…

Improving treatment of severe major depressive disorder by reducing negative future-oriented mental imagery

The primary aim of this pilot study is to determine the acceptability of the intervention. The secondary aim is to elucidate factors that may facilitate or hinder the feasibility of the follow-up RCT (e.g., recruitment process) and to estimate the…

Feasibility and to explore the effect of biofeedback gait training on the GRAIL in clubfoot patients, over 4 years of age, with a mild relapse

Is biofeedback gait training on the Gait Real Time Interactive Lab (GRAIL) feasible in children with mild recurrent clubfoot over 4 years of age? And to explore the effect in achieving clinically relevant immediate and short-term improvements in…