25 results
PROFITS aims to improve prognostic models for functional outcome in a broad cohort of 160 stroke patients. PROFITS will:1) Uniformly assess determinants for recovery of functional outcome starting in the first week after stroke and functional…
We aim to test the effectiveness of a patient-targeted preparatory tool (*Gesprekswijzer*) and an oncologist-targeted communication skills training to enhance shared decision making in consultations about palliative systemic treatment. The primary…
The primary objective is to study the effect of sensor monitoring embedded in an OT rehabilitation program for older persons after hip fracture on recovery of daily functioning, 6 months after the start of rehabilitation, as compared to coaching by…
The main objective of this research is to contribute to the elimination of disparities in care between Dutch and non-Dutch kidney patients where living donation is concerned. The primary objective is evaluating the effectiveness of an intervention…
The main objective is to study the effect of a pro-active, multi-component, nurse-led transitional care program until six months after hospital admission on ADL functioning. Secondary objectives are:To assess the effects of a pro-active, multi-…
Our pragmatic trial aims to integrate a cost-effective innovative care intervention in regular primary care. The intervention needs to be adapted for practice nurses to detect mental health problems in physical chronic patients and to provide,…
The aim of this study is to evaluate an intervention aimed at improving family disclosure of inherited cancer risks by 1) supporting counselees in what they experience as a necessary, but at times difficult, task and, consequently 2) provide more at…
The aim of this study is to examine the effectiveness of the IMR program compared to care as usual (CAU) in patients with SMI.
To examine the cost-effectiveness of a treatment protocol focused on self management rehabilitation followed by replacement in primary care for patients with chronic depression and/or anxiety who are currently being treated in secondary care.
The primary objective of this study is to evaluate the effectiveness of an ESM-based intervention, called *Partner in Zicht* to increase spousal caregiver competence and feelings of control in managing daily challenges. Increased caregiver…
To evaluate the benefits, risks and costs of laparoscopic gastrectomy as an alternative to open gastrectomy (gold standard) as treatment for gastric cancer in a Western population.
Primary objectiveThe primary objective is to assess the organizational and financial feasibility of implementation of the DLAM-treatment programme for T2D patients in primary care. This includes an observational cost-benefit analysis, informing…
The aim of our project is to establish the feasibility, effectiveness, costs and acceptance of early case finding of CD in children attending the YHCCs in a well described region in the Netherlands, using a POC test for TG2A determination.…
The primary objective is to assess the long-term (5-8 years) quality of life in patients who previously participated in the placebo-controlled randomized controlled trial on the effect of prolonged antibiotic treatment on persistent symptoms…
To assess the efficacy, safety and cost-effectiveness of the CYP2C19 genotype guided antiplatelet treatment strategy, using clopidogrel or prasugrel/ticagrelor.
Physical ExeRcise Following Esophageal Cancer Treatment (PERFECT) Study: a randomized clinical trial
Primary Objective: - To investigate whether a 12-week exercise intervention increases HRQoL in patients after curatively intended EC surgery compared to a usual care control group.Secondary Objective(s): - To investigate whether a 12-week exercise…
Within the present project we aim for a structural evaluation and registration of multidimensional clinical and geriatric data in all older patients with CKD stage IV and V, who will progress to ESRD, as proposed in the above mentioned guidelines.…
To determine whether it is feasible in practice to optimally monitor and treat patients with COVID-19 (Utrecht: CA-ARTI) in the home setting by using an intervention that is widely supported in the region.
The above mentioned developments are subject to the I CARE study. We hypothesize that general practitioner (GP) involvement improves both aftercare and preventive care resulting in improved quality of life and patients* satisfaction. Furthermore, a…
To assess whether the use of the personalized risk assessment tool (PERSARC) is (cost)effective in reducing decisional conflict and increasing informed choices in high-grade extremity STS compared to usual care (co-primary outcomes). In addition, we…