88 results
To determine whether early goal-directed therapy, aimed at optimizing cardiac output measured by arterial waveform analysis, improves outcome in high-risk, abdominal surgery.
To study the effect of individualized nutritional counselling compared to usual nutritional care on cross-sectional muscle area in patients with stage IV colorectal cancer during first-line chemotherapy. Secondary, effect on total lean body mass,…
Primary objective • To determine the overall response rate of two PHP with an at least 6 week interval and 3 mg/kg melphalan in irresectable liver metastases patients. • To determine the percentage of patients qualifying for resection. Secondary…
To examine if intravenous administration of iron ismore efficacious than oral iron in improvement offitness scores, iron status and reduction of fatigue
By relating valid learning fMRI phenotypes to the earliest expression of psychopathology and response to non-pharmacological self-management treatment, the project will contribute to the new innovative field of practical neuroimaging in the earliest…
The primary objective of the present study is to demonstrate that NT-proBNP guidance during in-hospital treatment for acutely decompensated heart failure (to strive for >30% reduction) reduces readmissions and mortality and increases the…
The objective of the study is to obtain information on the bioavailability and pharmacokinetics of the phenolics present in an olive leaf extract (Bonolive®, dose 250 mg), standardized on 40% oleuropein, and to identify the composition of the…
Primary Objective• To validate the existing demarcation formula (consisting of psychometric and biological markers) which predicts the sensitivity to Lybrido or Lybridos in women with female sexual interest/arousal disorder (FSIAD with or without…
The objective of this study is to determine the optimal myo-electric prosthesis training for obtaining the largest transfer effect. Here fore we plan to execute three experiments. At first it needs to be revealed which trainingtasks leads to the…
Measuring the effects of CO2 inhalation (6, 8 and 10%) on the body: EEG, heart rate, blood pressure, cardiac output, ECG, oxygen content in the brain, sedation, cognition, nausea.Amendment:Measuring the effects of CO2 inhalation (10% and 12%) on the…
In this study the effectiveness of online cognitive flexibility training on cognitive functioning in stroke patients will be investigated. The aim of this study is to improve executive functions: both trained executive functions as well as untrained…
To evaluate whether doxepin hydrochloride 5% cream is more effective in reducing pruritus in burn patients than standard treatment (clemastine).
In this study we will identify the role of the endothelial GAGs in Na+ and volume homeostasis. Is there a link between the ESL and an individual its susceptibility to Na+-excess?In a following study the Na+ buffering capacity of the intact ESL will…
The objective of our study is to to assess the diagnostic performance of 7T CE breast MRI in comparison to the current clinical standard of 3T MRI and histopathology on a intra-individual basis.
The primary objective is to investigate which balance and reaching performance measures - estimated using body-mounted sensing - correlate with frequently used clinical assessments of balance and motor function, while measuring stroke patients in a…
a. To establish the effects of (1) body weight support (2) treadmill speed, and (3) level of movement guidance provided by the exoskeleton on the neuromuscular control of the lower extremities.b. To establish the interactions between the above…
Assessment of the diagnostic accuracy of CTA for the detection of vasospasm after SAH in comparison to TCD.
Determine the safety and efficacy of Tiscover compared to AS210 (acellular donor dermis, construct Tiscover is cultured on) for the treatment of chronic, therapy resistant (arterio-) veneus leg/foot ulcers in an out patient setting.
To test the efficacy of renal sympathetic denervation therapy with a special focus on preservation of renal allograft function.
The main research question of this study is: 1. Does CBITlead to a reduction of fatigue severity in adult patients with CFS compared to a waiting list condition? Secondary research questions for phase one of the study: 2. Does CBIT lead to a…