108 results
There is evidence however that abdominal wall blocks, such as TAP blocks, could help managing the postoperative pain, but covering the visceral pain is not possible with this technique. It is not even clear to date which component of pain, the…
Primary objectiveThe primary objective is to assess the organizational and financial feasibility of implementation of the DLAM-treatment programme for T2D patients in primary care. This includes an observational cost-benefit analysis, informing…
The primary objective of this study is to compare the changes in neuromuscular control related to reactive and adaptive movements during balance and gait, following Dynamic C-mill Training to conventional physiotherapy. Furthermore, an additional…
The purpose of our study is to test the effect of a computer-based cognitive behavioral intervention (called Cognitive Bias Modification, CBM) on affective symptoms in oncology patients. Here we are collaborating with the Oncology department of the…
Primary Objective: To assess the effect of early extra measles immunization on the humoral immunity against measles 6 years after MMR-1 at 14 months of ageSecondary Objective(s): •Determine the effect of early extra measles immunization on the…
The aim of the study is investigate the feasibility of same day discharge supported by live video consultation and remote monitoring in a selected group of bariatric patients.
To investigate in our defined HF patient population if monitoring in combination with motivation on physical activity leads to an increase in enrollment rate for cardiac rehabilitation and sustained physical activity after cardiac rehabilitation as…
The objective is to study the effect of tart cherry juice on adipose tissue markers of oxidative stress, inflammation and macrophage infiltration, gene expression, visceral fat mass and analysis of the gut microbiome.
Evaluation of the AF detection performance of the BioMonitor III ICM in patients who are scheduled for a PVI in comparison to simultaneous Holter monitoring.
Primary research question:- Does treatment with drugs modulating vasoconstriction, i.e. COX-inhibitors (acetaminophen) or calcium-antagonists (nimodipine), improve electrographic postictal phenomena?Secondary research questions:- Does treatment with…
This study has been transitioned to CTIS with ID 2024-517267-23-00 check the CTIS register for the current data. The aim of this research is to investigate whether it is feasible and safe to pre-operatively treat patients who will undergo a distal…
Part 1:To determine the effect of depth of anaesthesia, as quantified by pEEG, on the quality of Tc-MEP measurements during spinal surgery.Hypothesis: lower depth of anaesthesia, defined by higher values of pEEG will:a. Decrease the threshold…
The main research objectives for the proof-of-concept study are to show the feasibility and safety of a daily cycle of feeding and fasting in critically ill children of different age-groups, that will trigger an adequate fasting response while…
Part A: Determine safety and tolerability of FTX-1821 in healthy subjects. Part B and C: Determine safety and tolerability of FTX-1821 in FSHD patients.
The main aim of the current study is to investigate the effect of a 12 week dietary intervention focusing on increasing vegetable intake on 24h blood pressure. Besides, we want to investigate the effects on:- Plasma concentrations: plasma nitrate…
Primary objective: To evaluate the efficacy of JNJ-68284528 (Phase 2)Secondary objectives:# To characterize the safety of JNJ-68284528 (Phase 2)# To characterize the pharmacokinetics and pharmacodynamics of JNJ-68284528# To assess the immunogenicity…
To test if diagnostic quality of radiography with portable devices is non-inferior to that of radiography with wall mounted devices.
The purpose of this study is to investigate how quickly and to what extent JNJ-64417184 is absorbed, distributed, metabolized and eliminated from the body. The pharmacokinetics of JNJ-64417184 when it is administered in the morning following the…
In Part 1 of the study, a fixed dose of ABBV-3067 (potentiator) will be co-administered with ABBV-2222 (corrector) in a dose range-finding manner to enable a dose selection for ABBV-2222 for Part 2 and future combination studies. In addition, ABBV-…
To assess image quality of MR-STAT-generated synthetic image data sets in patients with neurological diseases (primary objective), and compare image quality of these synthetic images with those acquired individually according to standard clinical…