175 results
The primary objective is to assess the effect of the parenting support intervention on parental stress. Secondary objectives are the effect of theintervention on other parental outcomes (anxiety and depression, satisfaction with the parental role,…
Primary Objective: To compare the effects of hypothyroidism and hyperthyroidism on cardiac left ventricular function, as assessed by CMR, in subjects with differentiated thyroid cancer during their early treatment.Secondary Objective(s): To compare…
The main aim of the study will be to compare the urinary N-nitroso compounds levels after intake of 70 ml of concentrated red beetroot juice containing 400 mg nitrate either with or without supplementation with 1 g vitamin C.
The objective of the study is to study the effect of Teripratide (rhPTH 1-34) on undercarboxylated osteocalcin levels, testosterone concentrations, glucose tolerance and insulin sensitivity in male subjects with primary osteoporosis.
The primary aim of this study is to find the dose of DHA during pregnancy and lactation that leads to a mean breastmilk DHA of at least 0.7g%.
We hypothesize that a smoking cessation strategy for smoking cervical cancer screening participants will increase their motivation to quit and will lead to an increased proportion of smokers performing a serious quit attempt. Eventually this will…
To unravel the cause(s) of the FH phenotype in patients with no mutations in well-established lipid genes (LDLR, APOB, PCSK9).
By relating valid learning fMRI phenotypes to the earliest expression of psychopathology and response to non-pharmacological self-management treatment, the project will contribute to the new innovative field of practical neuroimaging in the earliest…
To objective of this protocol is threefold.1. To investigate transdiagnostic cognitive deficits across a diversity of different psychiatric disorders.2. To link cognitive deficits with symptom-dimensions, EEG, cortisol, genetic and other blood…
The main objective of this study is to assess the ability of a wearable measurement system, the Hexoskin smart shirt, to detect and quantify dynamic hyperinflation. Secondary objectives are to determine the optimal measurement procedure and to…
The SIMBA project is a research collaboration in which children with asthma, their parents and healthcare professionals play an important role. The SIMBA study is a two year program that aims to develop and finally (pilot) test an exercise game that…
The objective of the proposed experiments is to study the effect of lighting intensity and spectral composition (correlated colour temperature) on thermal comfort and thermo physiology. The obtained insights can be used to improve thermal comfort,…
We hypothesize that formerly pre-eclamptic women have persistently increased angiotensin II sensitivity, sodium sensitivity, insulin resistance and sympathetic nerve activity together initially leading to susceptibility for early renal disease and…
The goal of the research is to apply balance perturbations during standing and walking, and capture the resulting stepping responses. These data will be used to develop and verify predictive models of foot placement. Such models might eventually be…
To study whether positioning influences RD progression.
1. To study thermoregulatory behavior and thermo-physiology of healthy lean and obese subjects before and after mild heat acclimation. 2. To define categories of *temperature preference* based on thermoregulatory behavior and thermo-physiology of…
The Claret device (Claret Inc.) is an Embolic Protection Device (EPD) consisting of two nitinol baskets to be introduced through the right radial artery. One basket is positioned in the brachiocephalic trunk, the other in the left common carotid…
In this study we will identify the role of the endothelial GAGs in Na+ and volume homeostasis. Is there a link between the ESL and an individual its susceptibility to Na+-excess?In a following study the Na+ buffering capacity of the intact ESL will…
The main objective of the study is to document cardiovascular dysfunction found in rheumatoid arthritis and gout patients using cardiac imaging techniques echocardiography and cardiac MRI.
The primary aim of this study is to validate the paradigms designed to investigate the effects of social stress and reward on in healthy individuals. This will allow us to evaluate and optimize the experimental paradigms in terms of their design,…