82 results
The primary objective of this randomized controlled trial is to evaluate the effectiveness of sensory nerve coaptation in autologous breast reconstructions on the sensibility of the reconstructed breast, compared to spontaneous sensory recovery, and…
Determine the frequency, phenotype and function of disorder-related immune cells, or levels of immune molecules in skin and peripheral blood of patients with inflammatory skin diseases, during the active phase of disease prior to and/or at any time…
Primary: Is OIT with standard food products safe to perform in children aged 9 to 24 months with a proven food allergy for hen's egg, peanut, cow's milk, cashewnut, hazelnut, walnut and/or one of the more rare allergens (as soy, pits and…
To study the direct effects of long-term intermittent fasting on immune cell populations in the blood, combined with analyses of systemic metabolic fitness and inflammatory activation of leukocytes.
Primary objectives:To prospectively assess longitudinal changes in Proteolipid Protein 1 (PLP1) and additional disease-related biomarkers in cerebral spinal fluid (CSF) and blood and evaluate their utility in support of the development of therapies…
Evaluation of the effect of different treatment thresholds in a clinical pathway for children with acute asthma who are treated with supplemental oxygen
The objective of this prospective randomized controlled trial is to compare the outcomes of arthroscopic primary repair of proximal ACL tears with the current gold standard of ACL reconstruction.
To study the most relevant outcome measures and a cost-effectiveness analysis of laparoscopic PIRS technique compared to open hernia repair in infants aged 6 months to 16 years of age with a primary unilateral inguinal hernia
The aim of this study is to compare treatment with an abduction device to active monitoring of infants with centered dysplastic hips (Graf type IIa- or IIb or IIc) during the first year of life.
Our main aim is to test the effectiveness of a personalized sport intervention, which aims to promote social integration through sport activities in the community.
To assess whether 10 sessions of cTBS of the contralesional primary motor cortex combined with regular care upper limb training, started within three weeks after stroke onset, are effective and cost effective in promoting upper limb recovery after…
The current study aims to obtain a better understanding of glymphatic dysfunction in dementia of the Alzheimer*s type and its preclinical stages.The main objective of this study is to improve our understanding of the potential link between…
The main objective of this study is to investigate the acute beneficial effect of moderate inten-sive exercise (defined as walking) on neurocognitive functioning in healthy children and adults with mild CP, GMFCS I and II and if this effect is…
To determine which biological processes play an essential role in immune-pathological changes in vitiligo skin depigmentation.
The primary objective of the study is to assess the longitudinal effects of differences and changes in renal function at CKD stage 3-5 on physical functioning. The secondary objectives of the study are to assess the longitudinal effects of…
To replicate the DEPREDICT algorithm (formed from external cohorts/datasets) as a valid tool for prediction of AD treatment non-response, we aim to recruit 80 patients who are treat-ed with an SSRI or SNRI and are eligible and willing to have an MRI…
We propose to set up a bladder cancer infrastructure within the logistic framework of the NCR. Patients with HR-NMIBC, MIBC and mBC will be prospectively recruited for ProBCI with longitudinal assessments from primary diagnosis until death. Main…
The primary objectives are to study the feasibility and acceptability of an 8-week daily oral supplementation with tributyrin (4 g/day) - the triglyceride form of butyric acid - on top of treatment as usual (TAU) in adults (18 up to 65 years) with…
The main objective of this study is to observe current AE treatment strategies and the treatment response of these strategies after 2 weeks in several hospitals. Secondary objectives are (1) to measure effect treatment on FeNO, eosinophils and…
To investigate the effect of nutritional prehabilitation on adverse events in patients with locoregionally advanced head and neck cancer, with low to medium risk of malnutrition and with radiological sarcopenia. To evaluate its effect on patient-…