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Imaging tumor-infiltrating CD8+ T-cells in non-small cell lung cancer upon neo-adjuvant treatment with Durvalumab (MEDI4736).

The overall aim of this study is to demonstrate increase of tumor-infiltrating CD8+ T cells in non-small cell lung cancer during neo-adjuvant treatment with durvalumab (MEDI4736).

The effect of non-invasive transauricular vagus nerve stimulation on upper gastrointestinal motility in healthy individuals

To study the impact of tVNS on gut motor function, in particular with regards to its potential to induce phase III contractions in the upper GI tract, in healthy subjects.

Bidirectional treatment consisting of repetitive laparoscopic electrostatic pressurized intraperitoneal aerosol chemotherapy with oxaliplatin (ePIPAC-OX) and systemic intravenous chemotherapy for isolated unresectable colorectal peritoneal metastases: feasibility, safety, tolerability, and preliminary efficacy.

To determine the safety, feasibility, and tolerability of adding PIPAC with oxaliplatin (92 mg/m2) to systemic chemotherapy in patients with isolated PM from CRC.

NL86996.000.24

Publication withdrawn by sponsor

PIWIL1 ISH ASSAY CLINICAL PERFORMANCE STUDY IN FFPE SPECIMENS FROM SUBJECTS WITH ADVANCED TUMORS FOR ENROLMENT WITHIN THE CLINICAL TRIAL IMC-R117C-1004

To evaluate the clinical utility of the PIWIL1 ISH assay for predicting response of patients with Advanced PIWIL1-Positive Cancers within the lmmunocore clinical study. To determine the role of PIWIL1 expression as a potential predictor of efficacy…