145 results
Primary objectives:- To assess the differences in resting state EEG frequency spectrum analysis between patients with neurodegenerative and patients with non-neurological causes of MCI.* Power in microvolts squared of resting stage EEG for different…
2 OBJECTIVES2.1 Primary Objective: To address the existing knowledge gaps and advance our understanding of cognitive variability, the CODEC study aims to integrate experience sampling methods, longitudinal designs, deep phenotyping cohorts, and…
The aim of this study is to evaluate if a PPT can significantly decrease - or possibly prevent - the collapse of the trachea in newborns with EA and moderate or severe TM. Additionally, the study aims to determine whether the observed effect of PPT…
The aim of this study is to validate the ultrasonographic hepatorenal index in children with overweight, obesity and morbid obesity, by using MRS.
Objective: To collect patient-reported symptoms, device data, and the clinical follow-up action of each remote transmission to develop an automated triage workflow that can discriminate between actionable and nonactionable evaluations. In addition,…
To investigate in healthy individuals not having ELP whether DUS and dynamic MRI may reveal a compressed popliteal artery in rest and during provocative testing (pointing, plantar foot flexion).
The primary objective of this study is to evaluate the efficacy of the AtMoves Knee System in the clinical diagnostic process of aseptic knee loosening in knee prostheses. This will be measured by the number of *failed outcomes* resulting from…
Primary objective: Determine correlation between RFS parameters (5 independent signal characteristics) and non-invasive hemodynamic parameters (estimated left ventricular end diastolic pressure, left ventricular ejection fraction, left ventricular…
Primary objective of this clinical investigation is to evaluate superiority of the signal quality of SOFT ECoG flexible high-density electrode grids compared to regular high-density electrode grids, routinely used at the UMC Utrecht. The signal…
Our central hypothesis is that the RNA content of TEPs allows for the identification of glioblastoma progression, including the differentiation from pseudo-progression and radionecrosis. For this we plan to use two parallel approaches, i.e. the TEP-…
We aim to determine the added value of a direct FET-PET for clinical practice. The hypothesis is that the addition of FET-PET will lead to correct diagnosis more rapidly than regular MRI alone, and thus to a better quality of life for patients…
To ascertain differences in mitochondrial and microcirculatory parameters between healthy older adults (> 65 years and ASA1-2) and more vulnerable elderly patients (> 65 years and ASA 3-4).
Primary objective: describe the longitudinal changes of Aβ38, Aβ40, Aβ42, and Aβ43 concentrations in CSF of patients with CAA, AD, and healthy control cases and estimate the differences in change between those groups.1. Explorative study to…
The primary aim of this study is to evaluate 3 techniques (CEUS, 3D and SMI), that can perhaps improve the ultrasound assessment of GCA with regard to its diagnostic value when applied alone or in combination. The hypothesis is that the diagnostic…
We want to show in the current pilot trial that the current market ready automated device is safe and effective to use in humans as the proof of principle prototype, as well as check the instructions for use (IFU).
This study aims to (i) compare baseline NM-MRI signal between CHR-P individuals and healthy controls (HCs) and (ii) evaluate whether baseline NM-MRI signal can differentiate those CHR-P individuals who progress to psychosis within three years of…
Primary ObjectiveThe aim of this clinical part of the Body Barrier project is to produce data from metals that pass the mucosa-blood barrier and/or the blood-CFS barrier. The clinical data will be used to validate the multi-organ-on-chip platform to…
The primary objective of this project is to evaluate the differences between a wide variety of cardiac disease and healthy volunteers using novel echocardiographic techniques (LV SV-loops, 3D RV beutels and SWI) and relate these to patient…
To assess inter-individual and intra-individual variation in objective skin pigmentation measurement using non-invasive colorimetry and multispectral imaging in healthy individuals and patients with skin disease.
Primary Objective:The aim of this study is to evaluate whether the effect of PFMT on pelvic floor muscle strength could be detected via 4D ultrasonography strain measurements in patients with SUI. Secondary Objective(s)- To determine the…